Results 31 to 40 of about 1,760 (172)

Serotonin Receptors in Hippocampus

The Scientific World Journal, Volume 2012, Issue 1, 2012., 2012
Serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes are expressed in hippocampus, which implicates an intricate modulating system, considering that they can be localized as autosynaptic, presynaptic, and postsynaptic receptors ...
Laura Cristina Berumen, Angelina Rodríguez, Ricardo Miledi, Guadalupe García-Alcocer, Jerrel Yakel   +4 more
wiley   +1 more source

An Updated Bio‐Behavioral Profile of the Flinders Sensitive Line Rat: Reviewing the Findings of the Past Decade

Pharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT The Flinders sensitive line (FSL) rat is an accepted rodent model for depression that presents with strong face, construct, and predictive validity, thereby making it suitable to investigate novel antidepressant mechanisms. Despite the translatability of this model, available literature on this model has not been reviewed for more than ten ...
Stephan F. Steyn
wiley   +1 more source

Intracellular Loop 2 Peptides of the Human 5HT1a Receptor are Differential Activators of Gi

International Journal of Peptides, Volume 2012, Issue 1, 2012., 2012
Peptide mimics of intracellular loop 2 (ic2) of the human 5HT1a receptor have been studied with respect to their ability to inhibit agonist binding via interference with receptor‐G‐protein coupling. These peptides give shallow concentration‐effect relationships. Additionally, these peptides have been studied with respect to their ability to trigger the
Brian Hall, Carley Squires, Keith K. Parker, Piero Andrea Temussi   +3 more
wiley   +1 more source

Triptan treatment is associated with a higher number of red wine‐induced migraine episodes: An exploratory questionnaire‐based survey

Pain Practice, Volume 24, Issue 6, Page 832-838, July 2024.
Abstract Aim Diet, including foods and beverages, affects migraine. Conversely, the influence of migraine therapies on dietary habits is largely unknown. This study aimed at investigating the effects of triptan intake on foods and drinks consumed by adults with migraine with and/or without aura.
Laura Nedergaard, Maria Celine Martens, Michala Daniela Bach Christensen, Lanfranco Pellesi   +3 more
wiley   +1 more source

Differential Effect of the Dopamine D3 Agonist (±)‐7‐Hydroxy‐2‐(N,N‐di‐n‐propylamino) Tetralin (7‐OH‐DPAT) on Motor Activity between Adult Wistar and Sprague‐Dawley Rats after a Neonatal Ventral Hippocampus Lesion

International Journal of Medicinal Chemistry, Volume 2011, Issue 1, 2011., 2011
The neonatal ventral hippocampal lesion (nVHL) has been widely used as an animal model for schizophrenia. Rats with an nVHL show several delayed behavioral alterations that mimic some symptoms of schizophrenia. Sprague‐Dawley (SD) rats with an nVHL have a decrease in D3 receptors in limbic areas, but the expression of D3 receptors in Wistar (W) rats ...
Sonia Guzmán-Velázquez, Linda Garcés-Ramírez, Gonzalo Flores, Fidel De La Cruz, Sergio R. Zamudio, Maarten Reith   +5 more
wiley   +1 more source

Cardiovascular effects in the Sprague-Dawley rat of 8−hydroxy−2(di- N-propylamino) tetralin, a selective 5−hydroxytryptamine receptor agonist

, 1985
The intravenous administration of 8−hydroxy−2(di-N-propylamino) tetralin, a selective 5−HT receptor agonist, caused a biphasic blood pressure response and bradycardia in Sprague-Dawley rats.
K Gradin, A Pettersson, T Hedner, L E Arvidsson, S Hjorth, B Persson   +5 more
core   +1 more source

Marked increases in plasma catecholamine concentrations precede hypotension and bradycardia caused by 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) in conscious rats

, 1989
Plasma noradrenaline and adrenaline responses to 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT), a selective putative 5-HT1A receptor agonist, have been studied in conscious, freely moving rats.
Gyoroy Bagdy, Katalin Szemeredi, Dennis L Murphy   +2 more
core   +1 more source

Efeitos das injeções de agonistas e antagonistas gabaérgicos e agonistas serotonérgicos na concha do núcleo accumbens sobre comportamentos defensivos e ingestivos em ratos [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasA fim de estabelecer uma relacao funcional entre o controle dos comportamentos defensivos e ingestivos em ratos, esse ...
Lopes, Ana Paula Fraga
core  

Lack of stereoselectivity of 8-hydroxy-2(di-N-propylamino)tetralin-mediated inhibition of forskolin-stimulated adenylyl cyclase activity in human pre- and post-synaptic brain regions

, 2000
The stereoselectivity of the serotonin(1 A) (5-HT1 A) receptor compound 8-hydroxy-2(di-N-propylamino)tetralin (8-OH-DPAT) on forskolin-stimulated adenylyl cyclase activity was investigated in membranes from human 5-HT pre-synaptic (raphe nuclei) and post-
GIANNACCINI, GINO, Marazziti D, Giromella A, Bigazzi F, Cassano GB, Borsini F, PALEGO, LIONELLA, MAZZONI, MARIA ROSA, NACCARATO, ANTONIO GIUSEPPE, LUCACCHINI, ANTONIO   +9 more
core   +1 more source

Efeitos da administração sistêmica de 5-HT e 8-OH-DPAT sobre os estados de vigília e sono de pombos (Columba livia) [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em NeurociênciasInvestigar a participação dos mecanismos serotonérgicos sobre a regulação dos estados de sono e vigília em pombos ...
Hoeller, Alexandre Ademar
core