Results 91 to 100 of about 702,385 (334)

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Multidirectional Charge Separation in Self‐Assembled Aggregates of Perylenebisimide‐Porphyrin Bola‐Supra‐Amphiphiles

Angewandte Chemie, EarlyView.
Stable aggregates of a new hydrogen‐bond mediated porphyrin‐perylenebisimide (PBI) bola‐type supra‐amphiphile have been synthesized by lyophilization of solutions of both single molecules in THF/water mixtures, followed by redispersion in pure water. Cryogenic transmission electron microscopy verifies the spherical morphology.
Erik J. Schulze, Elena A. Mack, Christian L. Ritterhoff, Ufuk Borucu, Bernd Meyer, Dirk M. Guldi, Andreas Hirsch   +6 more
wiley   +2 more sources

Possibility to Biotransform Anthracyclines by Peroxidases Produced by Bjerkandera adusta CCBAS 930 with Reduction of Geno- and Cytotoxicity and Pro-Oxidative Activity [PDF]

, 2021
Kamila Rybczyńska‐Tkaczyk, Teresa Korniłłowicz-Kowalska, Konrad A. Szychowski   +2 more
openalex   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Origin of a Raman scattering peak generated in single-walled carbon nanotubes by X-ray irradiation and subsequent thermal annealing

AIP Advances, 2016
We have found that a Raman scattering (RS) peak around 1870 cm−1 was produced by the annealing of the X-ray irradiated film of single-walled carbon nanotubes (SWNTs) at 450 oC.
Toshiya Murakami, Mitsuaki Matsuda, Kenji Kisoda, Chihiro Itoh   +3 more
doaj   +1 more source

Activation of Proteinase-Activated Receptors Induces Itch-Associated Response Through Histamine-Dependent and -Independent Pathways in Mice

Journal of Pharmacological Sciences, 2008
Proteinase-activated receptor-2 (PAR2) participates in itch, but the role of the other subtypes of this receptor remain unknown. To investigate this issue, scratching, an itch-related behavior, was observed following intradermal injections of the ...
Kenichiro Tsujii, Tsugunobu Andoh, Jung-Bum Lee, Yasushi Kuraishi   +3 more
doaj   +1 more source

Device Performance of Emerging Photovoltaic Materials (Version 6)

Advanced Energy Materials, EarlyView.
Efficiency of single junction perovskite (circles), organic (hexagons), dye sensitized (pentagons), kesterite (diamonds), Sb2Se3 (right triangle), and AgBiS2 (left triangles) solar cells at emerging‐pv.org over the last decade. ABSTRACT This 6th annual Emerging PV Report surveys peer‐reviewed advances since August 2024 across perovskite, organic ...
Osbel Almora, Agustin O. Alvarez, Derya Baran, Carlos I. Cabrera, Luigi A. Castriotta, Bruno Ehrler, Sule Erten‐Ela, Kenjiro Fukuda, Fei Guo, Jens Hauch, Anita W.Y. Ho‐Baillie, T. Jesper Jacobsson, Rene A. J. Janssen, Thomas Kirchartz, Maria A. Loi, Richard R. Lunt, Xavier Mathew, Jie Min, David B. Mitzi, Mohammad K. Nazeeruddin, Ana F. Nogueira, Ulrich W. Paetzold, Nam‐Gyu Park, Barry P. Rand, Henry Snaith, Takao Someya, Christian Sprau, Lulu Sun, Karen Forberich, Christoph J. Brabec   +29 more
wiley   +1 more source

Involvement of Tryptase and Proteinase-Activated Receptor-2 in Spontaneous Itch-Associated Response in Mice With Atopy-like Dermatitis

Journal of Pharmacological Sciences, 2009
This study investigated the involvement of tryptase and proteinase-activated receptor (PAR) subtypes in spontaneous scratching, an itch-associated behavior, in NC mice.
Kenichiro Tsujii, Tsugunobu Andoh, Haruna Ui, Jung-Bum Lee, Yasushi Kuraishi   +4 more
doaj   +1 more source

Experimental study of direct photon emission in K- --> pi- pi0 gamma decay using ISTRA+ detector

, 2004
The branching ratio in the charged-pion kinetic energy region of 55 to 90 MeV for the direct photon emission in the K- --> pi- pi0 gamma decay has been measured using in-flight decays detected with the ISTRA+ setup operating in the 25 GeV/c negative ...
A. P. Filin, A. S. Konstantinov, A. V. Inyakin, A. Yu. Polyarush, F. E. Low, G. Ecker, G. I. Britvich, H.-Y. Cheng, I. V. Ajinenko, I. V. Ajinenko, I. V. Ajinenko, I. Ya. Korolkov, J. Bijnens, J. D. Good, J. Wess, K. M. Smith, K. V. Datsko, M. A. Aliev, N. E. Smirnov, O. G. Tchikilev, O. P. Yushchenko, R. J. Abrams, S. A. Akimenko, S. Adler, S. L. Adler, S. V. Laptev, V. A. Duk, V. A. Khmelnikov, V. A. Polyakov, V. A. Uvarov, V. B. Anikeev, V. F. Konstantinov, V. F. Obraztsov, V. I. Romanovsky, V. I. Shelikhov, V. M. Leontiev, V. M. Ronjin, V. N. Bolotov, V. N. Bolotov, V. P. Novikov   +39 more
core   +1 more source

The Future of Hydrogen‐Powered Aviation: Technologies, Challenges, and a Strategic Roadmap for Sustainable Decarbonization

Advanced Energy and Sustainability Research, EarlyView.
Hydrogen‐powered aviation offers a transformative pathway to zero‐emission flight by eliminating in‐flight CO2 emissions. Key considerations include propulsion systems (fuel cells and hydrogen combustion), cryogenic storage and insulation challenges, infrastructure and cost barriers, and supply‐chain constraints.
Mubasshira, Md Mahbubur Rahman, Karib Hassan Khan, Md Nizam Uddin, Dewan Hafiz Nabil   +4 more
wiley   +1 more source