Results 251 to 260 of about 115,019,931 (299)

Activation of silent synapses driven by emerging technologies: mechanisms, disease associations, and prospects for clinical translation. [PDF]

Front Synaptic Neurosci
Li Y, Liao Y, Zhang S, Xu C, Lan R, Zhao P, Liu R, Song Y, Zhang X.   +8 more
europepmc   +1 more source

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

Equine Veterinary Journal, EarlyView.
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé, Jonathan Elliott, Nicola J. Menzies‐Gow, Simon R. Bailey, Nicholas J. Bamford, Yu‐Mei Chang, Matthew C. Gage   +6 more
wiley   +1 more source

Recent advances in the development of GRK2 inhibitors: blocking the interaction of GRK2 with its partners. [PDF]

Acta Pharmacol Sin
Han CC, Guo HZ, Guo FY, Tan HZ, Sun HZ, Gu JT, Zuo SJ, Wang WK, Ma Y, Wei W.   +9 more
europepmc   +1 more source

Extracellular vesicles derived from edible plants and edible fungi: Compositional characteristics, engineering strategies and biofunctions

Food Biomacromolecules, EarlyView.
Non‐animal extracellular vesicles as bioactive‐compound carriers: compositional characteristics, engineering strategies, and biofunctions. Abstract Animal‐derived extracellular vesicles (EVs) were widely used for bioactive compound delivery but constrained by complex origins, potential immunogenicity, and pathogen contamination.
Jiahao Yu, Rongheng Chen, Yuxuan Liu, Yizhen Xie, Fangyu Fan, Simin Feng, Ping Shao   +6 more
wiley   +1 more source

Canonical and Alternative Pathways (Insulin and Exercise) of GLUT4 Synthesis, Signaling, Intracellular Clustering, and Recruitment to the Plasma Membrane. [PDF]

Int J Mol Sci
Ramos-Jiménez A, Rubio-Valles M, Guereca-Arvizuo J, Juárez-Oropeza MA, Ramos-Hernández JA, Chávez-Guevara IA, González-Rodríguez E, Moreno-Brito V, Hernández Torres RP.   +8 more
europepmc   +1 more source

A disulfide bond sculpts the CTNIP4 phytocytokine fold for recognition by the receptor kinase HSL3. [PDF]

Nat Plants
Jiménez-Sandoval P, Johanndrees O, Snoeck S, Harshith CY, Omary M, Broyart C, Rhodes J, Bender KW, Zipfel C, Santiago J.   +9 more
europepmc   +1 more source

CD45 as a multifunctional target in immune regulation and therapeutic delivery. [PDF]

J Transl Med
Zhao K, Yang R, Li M, Zhang Z, Liu J, Shi J, Zhao X.   +6 more
europepmc   +1 more source

CDK1-mediated phosphorylation of EPLIN is crucial for mitotic spindle positioning. [PDF]

Commun Biol
Fan JR, Hsieh Y, Lai CC, Chen HC.
europepmc   +1 more source

Comment on Lin et al. Reconsidering Adipose Tissue Lipolysis Dysfunction: Evidence for a Distal Machinery Defect Beyond Insulin Resistance. [PDF]

Diabetes
Ragozzino G, Cantelli MT, Fulgione E, Mattera E.   +3 more
europepmc   +1 more source

Engineering Small Extracellular Vesicles for Colon-Targeted Delivery: Microenvironment-Responsive Design, Therapeutic Mechanisms, and Clinical Translation. [PDF]

Int J Nanomedicine
Liu G, Li M, Liu J, Li YP, Huang X, Guo X, Zhai Q, Zhang F, Yan W, Sun J.   +9 more
europepmc   +1 more source