Results 11 to 20 of about 2,894 (182)

a1-antitrypsin, a new biomarker of polycystic ovary syndrome by changing its expression and rhythm [PDF]

Journal of Ovarian Research
Background Previous proteomic studies have demonstrated the potential for identifying specific diagnostic biomarkers in the plasma and follicular fluid of patients with polycystic ovary syndrome (PCOS), which was utilized to elucidate the underlying ...
Na Li, Beilei Shen, Wei Cao, RouRou Chen, Rongbo He, Li Qian, Lin Xu, Yu Liu   +7 more
doaj   +2 more sources

Role of the alpha-1 antitrypsin in the progression and severity of COVID-19 infection among Saudi patients [PDF]

BMC Infectious Diseases
Background Alpha-1 antitrypsin (A1AT) is involved in pathophysiology of severe COVID-19, including thrombosis expansion. A1AT has anti-inflammatory, tissue-protective, and anticoagulant capabilities.
Rabab A. Ali, Walaa A. Mohammedsaeed, Mohamed Hisham A. Fakher, Hala K. Noor, Yasir M. Al Qurashi   +4 more
doaj   +2 more sources

α1-Antitrypsin (SERPINA1; AAT; A1AT) [PDF]

Science-Business eXchange, 2010

  +6 more sources

Immunological and homeostatic pathways of alpha -1 antitrypsin: a new therapeutic potential [PDF]

Frontiers in Immunology
α -1 antitrypsin (A1AT) is a 52 kDa acute-phase glycoprotein belonging to the serine protease inhibitor superfamily (SERPIN). It is primarily synthesized by hepatocytes and to a lesser extent by monocytes, macrophages, intestinal epithelial cells, and ...
Carmen Mazzuca, Carmen Mazzuca, Laura Vitiello, Silvia Travaglini, Fatima Maurizi, Panaiotis Finamore, Simona Santangelo, Amelia Rigon, Marta Vadacca, Silvia Angeletti, Simone Scarlata   +10 more
doaj   +2 more sources

Purified A1AT holds promise as therapy for acute liver failure [PDF]

Nature Reviews Gastroenterology & Hepatology, 2014
Katrina Ray
openalex   +3 more sources

28 Alpha1 antitrypsin (A1AT) deficiency among patients with cystic fibrosis

Journal of Cystic Fibrosis, 2005

openalex   +2 more sources

Combination of alpha-1 antitrypsin (A1AT) and anti-TNFα as a neuroprotective strategy in the early stages after ischemic stroke. [PDF]

J Cereb Blood Flow Metab
García-Rodríguez P, Ramiro L, Simats A, Ma F, Rosell A, Montaner J.   +5 more
europepmc   +3 more sources

α1-Antitrypsin (AAT; A1AT; SERPINA1); histone deacetylase 7 (HDAC7) [PDF]

Science-Business eXchange, 2012

openalex   +2 more sources

Faculty Opinions recommendation of Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency. [PDF]

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2017
Craig P. Hersh
openalex   +2 more sources

Alpha1-antitrypsin counteracts heme-induced endothelial cell inflammatory activation, autophagy dysfunction and death

Redox Biology, 2021
Free heme toxicity in the vascular endothelium is critical for the pathogenesis of hemolytic disorders including sickle cell disease. In the current study, it is demonstrated that human alpha1-antitrypsin (A1AT), a serine protease inhibitor with high ...
Kukuh Madyaningrana, Vijith Vijayan, Christoph Nikolin, Abid Aljabri, Srinu Tumpara, Elena Korenbaum, Harshit Shah, Metodi Stankov, Heiko Fuchs, Sabina Janciauskiene, Stephan Immenschuh   +10 more
doaj   +1 more source