Results 41 to 50 of about 554,238 (248)

The Establishment of Independence and Creativity Value of Early Childhood at TPA Taman Belia Candi Semarang

open access: yesJournal of Nonformal Education, 2017
The problems of the research are (1) how the establishment of independence value of early childhood in TPA (one Daycare) of PAUD Taman Belia Candi Semarang city, (2) how the establishment of creativity value of early childhood in TPA (one Daycare) of ...
Embun Melati Widiasih   +2 more
doaj   +1 more source

Secretory Phospholipase A2

open access: yesBiological and Pharmaceutical Bulletin, 2004
Secretory phospholipase A2 (sPLA2) is a growing family of structurally related, disulfide-rich, low molecular weight, lipolytic enzymes with a His-Asp catalytic dyad. sPLA2s are distributed in a wide variety of vertebrate and invertebrate animals, plants, bacteria, and viruses, and there are 10 catalytically active sPLA2 isozymes in mammals.
Murakami, Makoto, Kudo, Ichiro
openaire   +3 more sources

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Krasnoyarsk. Transformation of the industrial territory of the EVRZ

open access: yesПроект Байкал
The article deals with the territory of the industrial architectural heritage of the Krasnoyarsk Electric Railway-Car Repair Plant (EVRZ) as a place of creation of a district of modern residential development with active city life.
Константин Исмагилов   +3 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Preface: 2nd COL4A1-A2 International Conference

open access: yesProceedings
The 2nd COL4A1-A2 International Conference took place on 10 February 2025, at the National Research Council (CNR) in Rome, Italy [...]
Simona Manodoro, Francesca Manodoro
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

A nationwide student survey on biochemistry learning resources in Italy

open access: yesFEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti   +4 more
wiley   +1 more source

The transformative potential of lipid nanoparticles tailored for acute myeloid leukemia immunotherapy

open access: yesFrontiers in Immunology
T-cell engagers and engineered cell therapies have yet to deliver the same spectacular results in acute myeloid leukemia (AML) that they have in other hematologic malignancies. In this review, we analyze the challenges with AML immunotherapy development,
Alexander Kamb, John S. Welch
doaj   +1 more source

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