Results 141 to 150 of about 36,160 (276)

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

British Journal of Pharmacology, EarlyView.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi, Annika A. Jüttner, Annique Claringbould, Rene de Vries, Ingrid M. Garrelds, Usha Musterd‐Bhaggoe, Bruno H. Stricker, Maryam Kavousi, A. H. Jan Danser, Fariba Ahmadizar, Anton J. M. Roks   +10 more
wiley   +1 more source

Identification of A1/A2 β-Casein Genotypes and Comparison of Their Digestive Properties

Shipin gongye ke-ji
A1 β-casein and A2 β-casein produce different substances after digestion due to differences in primary structure. To more comprehensively explore the possible biological activity effects on the human body, by analyzing and monitoring the changes of this ...
Shihang LI, Hongtao XU, Xiao LI, Meiling SUN, Xinyan YANG, Pengyu XIANG, Zhihao YANG, Chaoxin MAN, Yujun JIANG   +8 more
doaj   +1 more source

Innovation management in dairy cattle A2 milk production and marketing

Süt, memelilerin yavruları için ürettiği ve insan beslenmesinde önemli bir rol oynayan temel besin kaynağıdır. İnek sütü proteinleri, tarih boyunca çeşitli mutasyonlar geçirmiş ve bu mutasyonlar A1 ve A2 β-kazein olarak adlandırılan iki farklı protein ...
Çelik, Bilgin
core  

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

Cell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang, Juan He, Jing Zheng, Bing Shao, Lixin Shi, Miao Zhang   +5 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

A2 Milk Consumption: a Review of this Innovative Product in Agribusiness

Revista de Gestão Social e Ambiental
Objective: The objective of this study was to detail the consumption of A2 milk, describing it as a factor of innovation and differentiation in the dairy derivatives market.   Theoretical Framework: In this topic, the main concepts and theories that underpin the research are presented.
Carolina de Mattos Nogueira, Juliana Querino Goulart, Letícia de Oliveira, Jean Philippe Palma Révillion, Catia Letícia Corrêa Schneider   +4 more
openaire   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

First Strike: Description of the Events at the First Salmon Farm Affected by the 2025 Algal Bloom in Northern Norway

Journal of Fish Diseases, EarlyView.
ABSTRACT Harmful algal blooms (HABs) are a threat to fish welfare, occurring suddenly and unexpectedly causing significant consequences for fish and salmon farmers worldwide. Norwegian farmers have been facing this challenge at irregular intervals since the very beginning of the industry. This report describes the events on the first fish farm affected
Julie Seem, Mirjam Nikoline Petterson, Tore Seternes, Pål Furset Lader, Julie Christine Svendsen, Lars‐Johan Naustvoll, Lars Helge Stien   +6 more
wiley   +1 more source

A critique of Truswell's A2 milk review [PDF]

European Journal of Clinical Nutrition, 2005
openaire   +1 more source

Physicochemical and simulated gastric digestion properties of A1/A1, A1/ A2 and A2/A2 yoghurts

This study aimed to determine the physicochemical properties of yoghurts from skim milk containing either β-casein A1/A1, A1/A2 or A2/A2 and establish their behaviour during simulated gastric digestion.
Talita, A. Comunian, Andre, Brodkorb, Davor, Daniloski, Daniela, Freitas, Todor, Vasiljevic, Noel, A. McCarthy   +5 more
core