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The Characteristics of A1-A2 β-Caseins in Milk and Their Effects on Human Health
Despite positive effects on nutrition, it has been reported that milk causes allergic reactions and many health problems. Allergic reaction to milk is called lactose intolerance, but it is estimated that this is not caused by lactose, but by the β ...
Sema Yaman Fırıncıoğlu +1 more
doaj +1 more source
The A2 milk case: a critical review [PDF]
This review outlines a hypothesis that A1 one of the common variants of beta-casein, a major protein in cows milk could facilitate the immunological processes that lead to type I diabetes (DM-I). It was subsequently suggested that A1 beta-casein may also be a risk factor for coronary heart disease (CHD), based on between-country correlations of CHD ...
openaire +2 more sources
Detecting β-Casein Variation in Bovine Milk
In bovine species, β-casein (β-CN) is characterized by genetic polymorphism. The two most common protein variants are β-CN A2 (the original one) and A1, differing from A2 for one amino acid substitution (Pro67 to His67).
Anna Maria Caroli +3 more
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Research has shown that digestion of A1 β-casein (β-CN) affects gastrointestinal motility and opioid activity through the release of the peptide β-casomorphin-7 (β-CM7).
Lisa G. Hohmann +5 more
doaj +1 more source
Dietary proteins provide bioactive peptides, which are important for host gastrointestinal functions. We hypothesized that A2-type β-casein could provide gastrointestinal benefits and improve the immune and gut health.
Bin Liu +11 more
doaj +1 more source
PCR Based Genotyping of Lulu Cattle of Nepal for A1, A2 Type Beta-caseins [PDF]
Lulu is an indigenous breed of cattle (Bos taurus) found in high altitude regions of western Nepal. Population of Lulu cattle has been declining due to introgression with other exotic breeds to increase milk productivity.
Budhathoki, N. (Nabina) +7 more
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cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
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“A2 milk” authentication using isoelectric focusing and different PCR techniques
Genetic variants of milk proteins have attracted great interest for decades as they are related to important issues such as the composition and technological properties of milk. More recently, an "A1/A2 hypothesis" was developed saying that β-casein variant A1 may be a dietary risk factor for cardiovascular diseases, type 1 diabetes, sudden infant ...
Helmut K, Mayer +2 more
openaire +2 more sources
Comparison of PUFA profiles in the blood and in follicular fluid and its association with follicular dynamics after PGF2α induced luteolysis in dairy cows [PDF]
The objectives of the present study were to examine the fatty acid (FA) profiles in serum and in the follicular fluid (FF) and the association between polyunsaturated fatty acid level (PUFA) and follicular growth dynamics following induced luteolysis in ...
Adamov, Nikola +8 more
core +3 more sources
Hypothetico-deductivism: incomplete but not hopeless [PDF]
Alleged counter-examples deployed in Park (2004) against the account of selective hypothetico deductive confirmation offered in Gemes (1998) are shown to be ineffective.
Gemes, Ken
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