H5N1 outbreaks and enzootic influenza
Ongoing outbreaks of H5N1 avian influenza in migratory waterfowl, domestic poultry, and humans in Asia during the summer of 2005 present a continuing, protean pandemic threat. We review the zoonotic source of highly pathogenic H5N1 viruses and their genesis from their natural reservoirs. The acquisition of novel traits, including lethality to waterfowl,
Guan, Y, Webster, RG, Peiris, M, Chen, H
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Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo +42 more
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Lack of H5N1 Avian Influenza Transmission to Hospital Employees, Hanoi, 2004
To establish whether human-to-human transmission of influenza A H5N1 occurred in the healthcare setting in Vietnam, we conducted a cross-sectional seroprevalence survey among hospital employees exposed to 4 confirmed and 1 probable H5N1 case-patients or ...
Nguyen Thanh Liem, Wilina Lim
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Seasonal oscillation of human infection with influenza A/H5N1 in Egypt and Indonesia. [PDF]
As of June 22, 2011, influenza A/H5N1 has caused a reported 329 deaths and 562 cases in humans, typically attributed to contact with infected poultry. Influenza H5N1 has been described as seasonal.
Eleanor J Murray, Stephen S Morse
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H5N1 influenza and the implications for Europe [PDF]
In the 20th century, the world experienced three influenza A pandemics: “Spanish flu” claiming 20-40 million lives in 1918-9 and the “Asian flu” of 1957 and “Hong Kong flu” of 1968, each of which claimed 1-4 million lives.1 It might be about to face another.
Denis, Coulombier, Karl, Ekdahl
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Continuing evolution of highly pathogenic H5N1 viruses in Bangladeshi live poultry markets
Since November 2008, we have conducted active avian influenza surveillance in Bangladesh. Clades 2.2.2, 2.3.4.2, and 2.3.2.1a of highly pathogenic avian influenza H5N1 viruses have all been identified in Bangladeshi live poultry markets (LPMs), although,
Subrata Barman +14 more
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The H5N1 Moratorium Controversy and Debate [PDF]
The pause in gain-of-function experiments involving highly pathogenic avian influenza virus to dissect mechanisms of mammalian transmission and virulence is a historic moment for science. The scientific community and the greater society that it serves are currently engaged in a vigorous debate on whether and how to carry out experiments that could ...
Arturo Casadevall, Thomas Shenk
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Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. [PDF]
: Virus outbreaks have been found to be related to the concentration of a new class of genomic peptides, Replikins^1^. The eight genes of H5N1 influenza virus were analyzed for the distribution of Replikin Counts (number Replikins /100 amino acids) in 2 ...
Samuel Bogoch +2 more
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Co-circulation of influenza A(H5N1) and seasonal influenza viruses among humans and animals could lead to co-infections, reassortment, and emergence of novel viruses with pandemic potential. We assessed the timing of subtype H5N1 outbreaks among poultry,
Lizette O. Durand +10 more
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A single residue substitution in the receptor-binding domain of H5N1 hemagglutinin is critical for packaging into pseudotyped lentiviral particles [PDF]
© 2012 Tang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Shui-Ling Chu +38 more
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