A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses. [PDF]
Development of effective vaccines to prevent influenza, particularly highly pathogenic avian influenza (HPAI) caused by influenza A virus (IAV) subtype H5N1, is a challenging goal.
Lanying Du +14 more
doaj +1 more source
The H5N1 Manuscript Redaction Controversy [PDF]
Scientists are an argumentative bunch, and science is no stranger to controversy. Since the beginning of the scientific revolution, science has witnessed and engaged in great controversies, including heliocentrism, the theory of evolution, the N-ray affair, and most recently the debate over climate warming.
Arturo Casadevall, Thomas Shenk
openaire +3 more sources
Genetic characterization of 2008 reassortant influenza A virus (H5N1), Thailand
In January and November 2008, outbreaks of avian influenza have been reported in 4 provinces of Thailand. Eight Influenza A H5N1 viruses were recovered from these 2008 AI outbreaks and comprehensively characterized and analyzed for nucleotide identity ...
Wongphatcharachai Manoosak +13 more
doaj +1 more source
Working Safely with H5N1 Viruses [PDF]
ABSTRACT Research on H5N1 influenza viruses has received much attention recently due to the possible dangers associated with newly developed avian H5N1 viruses that were derived from highly pathogenic avian viruses and are now transmissible among ferrets via respiratory droplets.
openaire +3 more sources
Beyond Formal Agreements: EU Agencies' Cooperation with Third Countries
ABSTRACT Third countries' participation in European Union (EU) agencies is attracting increasing attention as venues for differentiated European integration. Research has started to vest into the host of formal agreements regulating this cooperation. However, regulatory outreach by EU agencies may be more important than it is stated de jure, as many ...
Thibaud Deruelle +2 more
wiley +1 more source
Concurrent Acquisition of a Single Nucleotide Polymorphism in Diverse Influenza H5N1 Clade 2.2 Sub-clades [PDF]
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1,2. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 3.
Hala M. Esmat +10 more
core
Concurrent Acquisition of a Single Nucleotide Polymorphism in Diverse Influenza H5N1 Clade 2.2 Sub-clades [PDF]
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997. The number of confirmed human cases now exceeds 300, and the associated Case Fatality Rate exceeds 60%.
Moustafa M. Mansour +17 more
core +2 more sources
Background A 2009 global influenza pandemic caused by a novel swine-origin H1N1 influenza A virus has posted an increasing threat of a potential pandemic by the highly pathogenic avian influenza (HPAI) H5N1 virus, driving us to develop an influenza ...
Yu Hong +11 more
doaj +1 more source
Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief +4 more
wiley +1 more source
Is avian influenza virus A(H5N1) a real threat to human health? [PDF]
The A(H5N1) influenza remains a disease of birds with a significant species barrier: in the presence of some tens million cases of infection in poultry--with a wide geographical spread--, only a few hundreds cases have occurred in humans.
E. Pariani +3 more
core +3 more sources

