Results 81 to 90 of about 113,965,924 (221)
Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley +1 more source
Epidemiology study and risk assessments of highly pathogenic avian influenza H5N1 in free flying birds in Thailand [PDF]
The highly pathogenic avian influenza virus H5N1 was the cause of a pandemic of avian influenza in poultry throughout many parts of the world. The role of wild birds in the transmission and cycling of this virus has been uncertain and the current study ...
Siengsanan-Lamont, Jarunee
core
Influenza H5N1 Virus of Birds Surrounding H5N1 Human Cases Have Specific Characteristics on the Matrix Protein [PDF]
The H5N1 influenza virus in Indonesia has caused more than 100 people died due to the virus infections. Cases in humans were mostly due to the virus spread from the infected birds.
SOEBANDRIO, AMIN +13 more
core +1 more source
If William Shakespeare had never lived, the plays he wrote would not exist. Someone might have written: To be or not to be, that is the question: But it most certainly would not have been followed with: Whether ’tis Nobler in the mind to suffer The Slings and Arrows of outrageous Fortune Or to take Arms against a Sea of troubles And by opposing end ...
openaire +1 more source
High‐Content CRISPR Screening: Methods and Applications
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang +6 more
wiley +1 more source
Pathobiology of avian influenza in wild bird species [PDF]
Avian influenza viruses, especially highly pathogenic avian influenza viruses (HPAIV), affect a wide range of species, including humans and have thus become a major concern for veterinary medicine and public health.
Bröjer, Caroline
core +1 more source
BackgroundThe threat posed by highly pathogenic avian influenza A H5N1 viruses to humans remains significant, given the continued occurrence of sporadic human cases (499 human cases in 15 countries) with a high case fatality rate (approximately 60%), the
Maria D Van Kerkhove +6 more
doaj +1 more source
Health Security: A Concept in Search of a Purpose
ABSTRACT Although the term “health security” is continuously gaining prominence and there are increasing calls to “strengthen” it, the term remains conceptually ambiguous. This ambiguity creates uncertainty about exactly what is being advanced in policy and practice when health security is invoked, and what consequences this has for priority‐setting in
Delaram Akhavein, Seye Abimbola
wiley +1 more source
Highly pathogenic avian influenza H5N1 is a threat to global public health as a natural pandemic causing agent but has recently been considered a bioterrorism concern.
David Banner, Alyson Ann Kelvin
doaj +1 more source
We describe the host response continuum for highly pathogenic avian influenza viruses (HPAIV), including the continuum of host responses to HPAIV infection and exposure based on the primary axis of host competence, ability to infect other hosts, and host vulnerability.
Johanna A. Harvey +9 more
wiley +1 more source

