Results 61 to 70 of about 493,106 (301)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A parameter uniform fitted mesh method for a weakly coupled system of two singularly perturbed convection-diffusion equations [PDF]

, 2018
In this paper, a boundary value problem for a singularly perturbed linear system of two second order ordinary differential equations of convection- diffusion type is considered on the interval [0, 1]. The components of the solution of this system exhibit
Kalaiselvan, Saravana Sankar, Miller, John J. H., Sigamani, Valarmathi   +2 more
core   +2 more sources

Supersymmetric Three-Form Flux Perturbations on $AdS_5$

, 2007
We consider warped type IIB supergravity solutions with three-form flux and ${\cal N}=1$ supersymmetry, which arise as the supergravity duals of confining gauge theories. We first work in a perturbation expansion around $AdS_5 \times S^5$, as in the work
A. Kehagias, B. de Wit, B. R. Greene, B. S. Acharya, C. S. Chan, C. Vafa, D. R. Morrison, E. Witten, H. J. Kim, H. Verlinde, I. R. Klebanov, I. R. Klebanov, I. R. Klebanov, I. R. Klebanov, J. Maldacena, J. Schwarz, J. Schwarz, Joseph Polchinski, K. Becker, K. Behrndt, K. Dasgupta, L. Girardello, L. Randall, L. Randall, M. Gunaydin, M. Strassler, Mariana Graña, N. Dorey, N. Dorey, P. Candelas, P. Howe, R. Donagi, S. Gukov, S. Kachru, S. S. Gubser, S. S. Gubser   +35 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Weak cosmic censorship conjecture in Einstein–Maxwell gravity with scalar hair

European Physical Journal C: Particles and Fields, 2020
In this paper, we focus on the weak cosmic censorship conjecture (WCCC) in the Einstein–Maxwell gravity sourced by a conformally coupled scalar field, where the black hole solution can carry a scalar hair apart from the conserved charges of the ...
Jie Jiang, Ming Zhang
doaj   +1 more source

Leading all-loop quantum contribution to the effective potential in general scalar field theory

Journal of High Energy Physics, 2023
The RG equation for the effective potential in the leading log (LL) approximation is constructed which is valid for an arbitrary scalar field theory in 4 dimensions.
D. I. Kazakov, R. M. Iakhibbaev, D. M. Tolkachev   +2 more
doaj   +1 more source

Nonlinear superhorizon curvature perturbation in generic single-field inflation

, 2013
We develop a theory of nonlinear cosmological perturbations on superhorizon scales for generic single-field inflation. Our inflaton is described by the Lagrangian of the form $W(X,\phi)-G(X,\phi)\Box\phi$ with $X=-\partial^{\mu}\phi\partial_{\mu}\phi/2$,
Kobayashi, Tsutomu, Takamizu, Yu-ichi
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Boundedness of solutions to a second-order periodic system with p-Laplacian and unbounded perturbation terms

Boundary Value Problems
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xiumei Xing, Haiyan Wang, Shaoyong Lai
openaire   +2 more sources

Delayed phenomenon of loss of stability of solutions in a second-order quasi-linear singularly perturbed boundary value problem with a turning point [PDF]

Boundary Value Problems, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhou, Zheyan, Shen, Jianhe
openaire   +2 more sources