Results 131 to 140 of about 234,152 (246)

Assembly–Energetics–Control (AEC) Design Framework for Rotary DNA Nanomachines

ChemBioChem, Volume 27, Issue 8, April 2026.
Rotary DNA nanomachine is an emerging research interest using DNA as building blocks to fabricate nature‐mimicking mechanisms. Here, we suggest a three‐dimensional conceptual framework to categorize the existing designs and identify underexplored directions.
Xue‐Yan Wang, Yicheng Heng, Julian A. Tanner, Simon Chi‐Chin Shiu   +3 more
wiley   +1 more source

The AAA+ ATPases and HflB/FtsH Proteases of ‘Candidatus Phytoplasma mali’: Phylogenetic Diversity, Membrane Topology, and Relationship to Strain Virulence

Molecular Plant-Microbe Interactions, 2013
Previous examination revealed a correlation of phytopathogenic data of ‘Candidatus Phytoplasma mali’ strains and the DNA sequence variability of a type ATP00464 hflB gene fragment. To further investigate such a relationship, all distinct genes previously
Erich Seemüller, Sandor Sule, Michael Kube, Wilhelm Jelkmann, Bernd Schneider   +4 more
doaj   +1 more source

Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase [PDF]

, 2017
Refolding aggregated proteins is essential in combating cellular proteotoxic stress. Together with Hsp70, Hsp100 chaperones, including Escherichia coli ClpB, form a powerful disaggregation machine that threads aggregated polypeptides through the central ...
Bukau, B., Carroni, Marta, Deville, Celia, Franke, K.B., Mogk, A., Saibil, Helen R., Topf, Maya   +6 more
core   +1 more source

The Effect of Free and Nanoliposomal Curcumin on the Viability and Acid Production of Single‐Species (Streptococcus mutans) and Polymicrobial Biofilms

Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objectives Dental caries is a global health concern caused by the formation of cariogenic biofilms and their acid production. While various approaches have been tried, the rise of antibiotic‐resistant microorganisms necessitates safer and more effective antimicrobial solutions.
Parisa Habibi, Farideh Tabatabaei Yazdi, Seyed Ali Mortazavi, Mohammad Morad Farajollahi   +3 more
wiley   +1 more source

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers

Nature Communications, 2016
The AAA+ ATPase p97 is an essential hexameric protein with multiple protein interaction partners and cellular functions. Here, the authors use interaction mapping to examine partner proteins of this large complex, and assess the effects of these proteins
Anup Arumughan, Yvette Roske, Carolin Barth, Laura Lleras Forero, Kenny Bravo-Rodriguez, Alexandra Redel, Simona Kostova, Erik McShane, Robert Opitz, Katja Faelber, Kirstin Rau, Thorsten Mielke, Oliver Daumke, Matthias Selbach, Elsa Sanchez-Garcia, Oliver Rocks, Daniela Panáková, Udo Heinemann, Erich E. Wanker   +18 more
doaj   +1 more source

Socializing, networking and development: a report from the second ‘Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis’ [PDF]

, 2012
In mid-June, the second Young Microbiologists Symposium took place under the broad title of ‘Microbe signalling, organization and pathogenesis’ on the picturesque campus of University College Cork, Ireland.
Barret, Brackman, Brown, Bush, Cascales, Corrigan, Costerton, Coulthurst, D'Autreaux, Davey, Delalez, Fazli, Gerlach, Hagan, Holland, Hood, Housden, Kleanthous, Kuchma, Kuchma, Kuchma, Lawley, Lebeer, Malone, McCarthy, Merritt, Murdoch, O'Connell Motherway, O'Connell Motherway, O'Toole, Porter, Ramsay, Ramsay, Rigel, Roberts, Ryan, Ryan, Ryan, Ryan, Ryan, Schwarz, Sharma, Shioya, Smith, Thompson, Twomey, Waters, Yang, Youle   +48 more
core   +1 more source

High‐Purity Functional Corneal Endothelial Cells From Human Induced Pluripotent Stem Cells via a Novel Wash‐Out Method

MedComm, Volume 7, Issue 4, April 2026.
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye, Changmin Kim, Minah Jeon, Yeji Yoon, Jiyoon Park, Ryun Hee Lee, Carson Yu, Ho Seok Chung, Jae Yong Kim, David Myung, Hun Lee   +10 more
wiley   +1 more source

Structural insights into the Escherichia coli lysine decarboxylases and molecular determinants of interaction with the AAA+ ATPase RavA

Scientific Reports, 2016
The inducible lysine decarboxylase LdcI is an important enterobacterial acid stress response enzyme whereas LdcC is its close paralogue thought to play mainly a metabolic role.
E. Kandiah, D. Carriel, J. Pérard, H. Malet, M. Bacia, Kaiyin Liu, S. W. S. Chan, W. Houry, S. Ollagnier de Choudens, S. Elsen, I. Gutsche   +10 more
semanticscholar   +1 more source

Ricin trafficking in plant and mammalian cells [PDF]

, 2011
Ricin is a heterodimeric plant protein that is potently toxic to mammalian and many other eukaryotic cells. It is synthesized and stored in the endosperm cells of maturing Ricinus communis seeds (castor beans).
Lord, Mike, Spooner, Robert A.
core   +2 more sources

Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases

eLife, 2019
Many AAA+ ATPases form hexamers that unfold protein substrates by translocating them through their central pore. Multiple structures have shown how a helical assembly of subunits binds a single strand of substrate, and indicate that translocation results
Han Han, James M Fulcher, Venkata P Dandey, Janet H Iwasa, Wesley I Sundquist, Michael S Kay, Peter S Shen, Christopher P Hill   +7 more
doaj   +1 more source