Results 211 to 220 of about 401,347 (255)

NorQD AAA+ complex drives metal insertion by a twisting mechanism. [PDF]

open access: yesNat Commun
Kahle M   +5 more
europepmc   +1 more source

Mitochondrial AAA+ proteases

2023
Mitochondria are multifunctional organelles that play a central role in a wide range of life-sustaining tasks in eukaryotic cells, including adenosine triphosphate (ATP) production, calcium storage and coenzyme generation pathways such as iron-sulfur cluster biosynthesis.
openaire   +2 more sources

AAA+ Proteases: ATP-Fueled Machines of Protein Destruction

Annual Review of Biochemistry, 2011
AAA+ family proteolytic machines (ClpXP, ClpAP, ClpCP, HslUV, Lon, FtsH, PAN/20S, and the 26S proteasome) perform protein quality control and are used in regulatory circuits in all cells. These machines contain a compartmental protease, with active sites sequestered in an interior chamber, and a hexameric ring of AAA+ ATPases.
Robert T, Sauer, Tania A, Baker
openaire   +2 more sources

Principles of AAA+ Proteases

2022
ATPases associated with diverse cellular activities (AAA+) proteases in bacteria help maintain protein homeostasis by degrading misfolded and regulatory proteins. While a handful of protein targets for these proteases have been identified in Caulobacter crescentus and other organisms, more research is needed to elucidate mechanisms that govern ...
openaire   +1 more source

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