Results 191 to 200 of about 121,774 (253)

The neutrophil-to-lymphocyte ratio is associated with adverse outcomes in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis. [PDF]

Front Immunol
Li Y, Liu Z, Zhang D, Sun Z, Zhang H, Xie L, Chen H, Cai C, Li Y, Jia J, Xu P.   +10 more
europepmc   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Prevalence and clinical outcomes of fibrotic interstitial lung disease in ANCA associated vasculitis: a single-centre, retrospective, cohort study. [PDF]

Respir Res
Tirelli C, Mira S, Schioppo T, Mirijaj S, Italia M, Pescol F, Frizzarin S, Albrici C, Alfano F, Sacchi L, Podda GM, Cozzolino MG, Mondoni M.   +12 more
europepmc   +1 more source

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions

Sensory Neuroscience, EarlyView.
ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang, Yu Xiao, Jiaxin Liu, Wen Jiang, Weiwei Shi, Hanbing Zhang, Xiaolong Fu, Yunhao Wu   +7 more
wiley   +1 more source

Modification and expansion of existing body condition scoring scales for rabbits (Oryctolagus cuniculus) improves inter‐rater reliability when used by experienced raters

Veterinary Record, EarlyView.
Abstract Background Reliable body condition scoring in rabbits is essential in managing healthy bodyweight. The commonly used Rabbit size‐o‐meter (RSOM) has shown poor inter‐rater reliability, particularly among inexperienced raters. This study aimed to develop a reliable, reproducible body condition scoring scale for companion rabbits across breeds ...
Mette L. Halck, Cecilie R. Skovlund, Kathrine Stenberg, Antonia V. Adji, Mia Albert, Mette H. Rasmussen, Charlotte R. Bjørnvad   +6 more
wiley   +1 more source

C/EBPβ Contributes to Cancer-Induced Bone Pain by Inhibiting CD200/CD200R1 in the Spinal Cord. [PDF]

CNS Neurosci Ther
Li DY, Liu L, Liu DQ, Zhang LQ, Zhou YQ, Mei W.   +5 more
europepmc   +1 more source

The Role of Kidney Biopsy as a Tool for Personalized Treatment Decision-Making in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Nephritis. [PDF]

J Pers Med
Harada M, Aso S, Nimura T, Yamaka K, Aomura D, Yamada A, Sonoda K, Yamaguchi A, Kamimura Y, Ichikawa T, Kobayashi M, Hashimoto K, Kamijo Y.   +12 more
europepmc   +1 more source

Integrative Mendelian randomization and experimental validation prioritize KLF4 in the gut microbiota-pyroptosis-barrier axis of ulcerative colitis. [PDF]

Front Immunol
Zhu W, Jin X, Guo X, Gao X.
europepmc   +1 more source