Results 191 to 200 of about 79,958 (292)

Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity. [PDF]

Elife
Masumura R, Goda K, Sekiguchi M, Uesaka N.   +3 more
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Progressive cerebral infarction as the presenting feature of ANCA-associated vasculitis with concurrent Evans syndrome: a case report and literature review. [PDF]

Front Immunol
Yuan H, Zhang T, Du M, Liang Z.
europepmc   +1 more source

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

Exploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen, Wenzhe Yi, Rongzhang Li, Shuangshuang Hu, Xindi Qian, Dan Yan, Qian Zou, Guanru Wang, Yaping Li   +8 more
wiley   +1 more source

Mitteilungen des AAV

core   +5 more sources

Development of an Agent-Based Model to Investigate Durability of Factor IX Activity in Hemophilia B Patients Treated With Etranacogene Dezaparvovec. [PDF]

CPT Pharmacometrics Syst Pharmacol
Li Y, Nandy P, Jordie E, Knab T, Peppel K, Kirouac DC, Wilkins AK, Nuthalapati S.   +7 more
europepmc   +1 more source

Abnormal Stress Reduced miR-330 Supplementation Alleviates Osteoarthritis Progression by Suppressing Osteochondral Catabolism. [PDF]

Aging Cell
Zou L, Yang K, Wang C, Yu Y, Zhang X, Lu C, Zhao J, Qin A, He D.   +8 more
europepmc   +1 more source

CRISPR-Cpf1-Mediated Gene-Editing System Based on a Single Bidirectional Promoter. [PDF]

Int J Mol Sci
Kim S, Kim GN, Jeong YJ, Cho J, Jang M, Hong J, Sung YH.   +6 more
europepmc   +1 more source

Clinical characteristics and predictors of in-hospital mortality in patients with ANCA-associated vasculitis complicated by diffuse alveolar hemorrhage: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Gao X, Wang X, Yu K, Yu Q, Que C, Wang G, Ma J.   +6 more
europepmc   +1 more source

AAV Immunogenicity: A Matter of Sensitivity [PDF]

Molecular Therapy, 2018
openaire   +3 more sources