Results 161 to 170 of about 507,524 (341)

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

open access: yesAdvanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou   +9 more
wiley   +1 more source

Sugar‐Armored Pesticides: Self‐Assembled System for Enhanced Foliar Adhesion and Sustained Delivery of Hydrophobic Antimicrobials Against Bacterial Diseases

open access: yesAdvanced Science, EarlyView.
This study develops a sugar‐armored, self‐assembled pesticide delivery system that enhances foliar adhesion, provides sustained release, effectively disrupts biofilms, and demonstrates superior bactericidal activity for improved disease control.
Jinghan Yang   +3 more
wiley   +1 more source

Reversing multidrug resistance in breast cancer cells by silencing ABC transporter genes with nanoparticle-facilitated delivery of target siRNAs

open access: yesInternational Journal of Nanomedicine, 2012
Yong Tsuey Li,1 Ming Jang Chua,1 Anil Philip Kunnath,1 Ezharul Hoque Chowdhury,1,21Faculty of Medicine and Health Science, International Medical University (IMU), No 126, Jalan 19/155B, Bukit Jalil, 57000 Kuala Lumpur, Malaysia; 2Jeffrey Cheah School of ...
Li YT, Chua MJ, Kunnath AP, Chowdhury EH
doaj  

Dual‐Strategy Design of Heterojunction‐Enhanced Piezoelectric Hydrogels for Periodontitis Treatment

open access: yesAdvanced Science, EarlyView.
This study developed a piezoelectric hydrogel integrating heterojunction enhancement and dual‐salt synergy, combining robust electrical performance with mechanical stability and bioactivity to better match the periodontal microenvironment. Under ultrasound activation, the hydrogel markedly promotes macrophage M2 polarization, thereby reducing the ...
Qiangqiang Zhou   +10 more
wiley   +1 more source

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

open access: yesAdvanced Science, EarlyView.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei   +7 more
wiley   +1 more source

Use of bioinformatics and PCR in the search for ABC transporter homology among various bacteria [PDF]

open access: yes, 2004
Bioinformatics databases and search tools are utilised to produce polymerase chain reaction (PCR) primers for the amplification of an ABC transporter gene from the clinically important anaerobe Finegoldia magna.
Greenwell, P.   +9 more
core  

Machine Learning for Designing Perovskites and Perovskite‐Inspired Solar Materials: Emerging Opportunities and Challenges

open access: yesAdvanced Science, EarlyView.
This review offers a comprehensive comparison between perovskites and perovskite‐inspired materials (PIMs), focusing on their crystal structures, electronic properties, and chemical compositions. It evaluates the applicability of machine learning (ML) descriptors and models across both material classes.
Yangfan Zhang   +6 more
wiley   +1 more source

A Putative ABC Transporter Confers Durable Resistance to Multiple Fungal Pathogens in Wheat

open access: yesScience, 2009
S. Krattinger   +8 more
semanticscholar   +1 more source

3D‐Printed Supramolecular Eutectogels—Tunable Conductive Wires for Soft Electric Circuits

open access: yesAdvanced Electronic Materials, EarlyView.
Soft, flexible gels based on self‐assembling low‐molecular‐weight gelators in deep eutectic solvents can be 3D‐printed into electrical circuits using a simple wet‐spinning approach, acting as tunable conducting components, and having potential future applications in bionanoelectronics.
Tajmon T. Vadukoote   +3 more
wiley   +1 more source

Structure and mechanotransmission mechanism of the MacB ABC transporter superfamily

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
A. Crow   +3 more
semanticscholar   +1 more source

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