Results 21 to 30 of about 507,524 (341)
Characterizing ABC-Transporter Substrate-Likeness Using a Clean-Slate Genetic Background
Frontiers in Pharmacology, 2019 Mutations in ATP Binding Cassette (ABC)-transporter genes can have major effects on the bioavailability and toxicity of the drugs that are ABC-transporter substrates.
Artem Sokolov +15 more
doaj +1 more source
Applied Sciences, 2022 Recent transcriptomic profiling has revealed importance membrane transporters such as ATP-binding cassette (ABC) transporters in fungal necrotrophic mycoparasites.
Seon Hwa Kim, Vladimir Vujanovic
doaj +1 more source
ABC-B transporter genes in Dirofilaria immitis
International Journal for Parasitology: Drugs and Drug Resistance, 2016 Dirofilaria immitis is a filarial nematode causing infection and heartworm disease in dogs and other canids, cats, and occasionally in humans. Prevention with macrocyclic lactones (ML) is recommended during the mosquito transmission season.
Catherine Bourguinat +4 more
doaj +1 more source
Expression pattern of the human ABC transporters in pluripotent embryonic stem cells and in their derivatives [PDF]
, 2014 Background: ATP-binding Cassette (ABC) transporters have key roles in various physiological functions as well as providing chemical defense and stress tolerance in human tissues.
Apáti, Ágota +10 more
core +1 more source
, 2012 ATP binding cassette proteins are a large and diverse family of molecular machines and include transmembrane transporter, chromosome maintenance and DNA repair proteins, and translation factors.
Karl-Peter Hopfner, Roy
core +1 more source
Phosphorylation is required for the pathogen defense function of the Arabidopsis PEN3 ABC transporter. [PDF]
, 2017 The Arabidopsis PEN3 ABC transporter accumulates at sites of pathogen detection, where it is involved in defense against a number of pathogens. Perception of PAMPs by pattern recognition receptors initiates recruitment of PEN3 and also leads to PEN3 ...
Somerville, Shauna, Underwood, William
core +1 more source
Microbial Cell Factories, 2009 Background ATP binding cassette (ABC) transporter secretes the protein through inner and outer membranes simultaneously in gram negative bacteria. Thermostable lipase (TliA) of Pseudomonas fluorescens SIK W1 is secreted through the ABC transporter.
Moon Yuseok +5 more
doaj +1 more source
Investigating the dynamic nature of the ABC transporters: ABCB1 and MsbA as examples for the potential synergies of MD theory and EPR applications [PDF]
, 2015 ABC transporters are primary active transporters found in all kingdoms of life. Human multidrug resistance transporter ABCB1, or P-glycoprotein, has an extremely broad substrate spectrum and confers resistance against chemotherapy drug treatment in ...
Abe +83 more
core +1 more source
Crystallization of the oligopeptide-binding protein AppA from Bacillus subtilis [PDF]
, 2004 AppA is the membrane-anchored extracellular receptor component of an ABC transporter responsible for the uptake of oligopeptides into Bacillus subtilis.
Blagova, E +6 more
core +1 more source