Results 231 to 240 of about 110,036 (294)

Patterns of help‐seeking for mental health problems in 1001 self‐identified neurodivergent adolescents who self‐harm

JCPP Advances, EarlyView.
Adolescents who self‐harm are also more likely to seek support from informal than formal sources and least likely to seek support online. But neurodivergent adolescents who self‐harm are more likely to seek any and especially formal (pastoral school staff or mental health services) support than their peers.
Simona Skripkauskaite, Galit Geulayov, the OxWell Study Team, Mina Fazel, Rohan Borschmann   +4 more
wiley   +1 more source

Probiotic consumption reduces alveolar bone loss and kidney damage in pregnant rats with experimental periodontitis

Journal of Periodontology, EarlyView.
Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre, Pedro H. F. Silva, Marina C. G. Del‐Arco, Raquel F. Gerlach, Rene S. Oliezer, José E. Tanus‐Santos, Luciene C. Figueiredo, Janaina S. A. M. Evangelista, Flávia A. C. Furlaneto, Michel R. Messora, Sérgio Luiz Salvador   +10 more
wiley   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

Journal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar, Jeba Mercy Gnanasekaran, Niyant Ganesh, Cindy Zhou, Amy Plotkin, Giacomo Baima, Massimo Costalonga, Fenfen Zhou, Hanping Feng, Priyam Jani, Jean‐Pierre Raufman, Vivek Thumbigere‐Math   +11 more
wiley   +1 more source

20(S)-Ginsenoside Rh2 overcomes gemcitabine resistance in pancreatic cancer by inhibiting LAMC2-Modulated ABC transporters. [PDF]

J Adv Res
Wu Y, Zhang J, Tian Y, Chi Shing Cho W, Xu HX, Lin ZX, Xian YF.   +6 more
europepmc   +1 more source

Sewage Sludge and Cashew Bagasse Biochars Promote Changes in Selected Physical Attributes Related to the Structure of Degraded Dryland Soil

Journal of Plant Nutrition and Soil Science, EarlyView.
This study evaluated biochars from co‐pyrolysis of sewage sludge and cashew residues on physical quality of a degraded loamy sand soil. SPB applied at 20 Mg ha−1 reduced bulk density by 7.74%, whereas most porosity attributes were driven by soil reconsolidation rather than biochar. Aggregate stability varied with biochar type, with SPB promoting larger
João Marcos Rodrigues dos Santos, Ícaro Vasconcelos do Nascimento, Gilvanete da Silva Henrique, Tiago da Costa Dantas Moniz, Francisco Luan Almeida Barbosa, Alexandre dos Santos Queiroz, Adriana Guirado Artur, Mirian Cristina Gomes Costa, Helon Hébano de Freitas Sousa, Odair Pastor Ferreira, Laís Gomes Fregolente, Antônio Gomes de Souza Filho, Romildo Lopes de Oliveira Filho, Arthur Prudêncio de Araujo Pereira, Jaedson Cláudio Anunciato Mota   +14 more
wiley   +1 more source

Deciphering the functional role of clinical mutations in ABCB1, ABCC1, and ABCG2 ABC transporters in endometrial cancer. [PDF]

Front Pharmacol
Gupta A, Singh MS, Singh B.
europepmc   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment. [PDF]

Front Pharmacol
Veit G, Matsuo M, Okiyoneda T.
europepmc   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Bright Ferritin for Non‐Invasive MRI Monitoring of the Fate of Transplanted hPSC‐Cardiomyocytes in the Infarcted Rat Heart

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang, Faisal J. Alibhai, Beiping Qiang, Rocco Romagnuolo, Kyle D. W. Vollett, Bradley K. C. Freeman, M. Juliana Gomez‐Garcia, Tamilla Sadikov Valdman, Tameshwar Ganesh, Yu‐Qing Zhou, Hai‐Ying Mary Cheng, Michael A. Laflamme, Hai‐Ling Margaret Cheng   +12 more
wiley   +1 more source