Results 221 to 230 of about 68,283 (287)

Chrysosplenetin acts as a homeostasis stabilizer with dual-function in shattering Plasmodium berghei K173 resistance to artemisinin driven by both ABC transporters and heme-ROS/GSH axis. [PDF]

Parasit Vectors
Ji H, Huang Y, Tian J, Bo R, Heng X, Yang J, Huang Y, Wang X, Tan Q, Gao H, Chen L, Chen J.   +11 more
europepmc   +1 more source

Organic electrochemical transistor‐based tactile perception: From sensing to neuromorphic processing

InfoMat, EarlyView.
Organic electrochemical transistors (OECTs) offer a unique platform for tactile perception electronics by coupling ionic and electronic transport. This review highlights recent advances in OECT‐based temperature and pressure sensing, emphasizing material design, device architectures, operating mechanisms, and fabrication strategies toward flexible ...
Xuefeng Zhang, Deliu Zeng, Runjie Zhang, Yu Xiao, Zerui Yu, Siyu Di, Guo Liu, Lianhong Shan, Lianrui Cheng, Xiaofang Wei, Fengjiao Zhang   +10 more
wiley   +1 more source

MiRNAs function in the development of resistance against doxorubicin in cancer cells: targeting ABC transporters. [PDF]

Front Pharmacol
Lu XY, Jin H.
europepmc   +1 more source

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

Interdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi, Min Chen, Yisheng Chen, MengYao Li, Jiale Ma, Zuozhen Yin, Li Wu, YangBao Miao, Zemin Ou, Ke Wu, Zhijie Xu, Lizhi Li, Shaocong Zhao, Shiwei He, Bin Huang, Guanwen He, Guanghui Wu, John H. Zhang, Liang Shi   +18 more
wiley   +1 more source

Growth Hormone Signaling in Bladder Cancer: Transcriptomic Profiling of Patient Samples and In Vitro Evidence of Therapy Resistance via ABC Transporters and EMT Activation. [PDF]

Int J Mol Sci
Davis E, Caggiano LJ, Munholland H, Basu R, Berryman DE, Kopchick JJ.   +5 more
europepmc   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Substrate-Induced Structural Dynamics and Evolutionary Linkage of Siderophore-Iron ABC Transporters of Mycobacterium tuberculosis. [PDF]

Medicina (Kaunas)
Farhana A, Alsrhani A, Ejaz H, Alruwaili M, Alameen AAM, Manni E, Rasheed Z, Khan YS.   +7 more
europepmc   +1 more source

Organizational and Functional Principles of the Obligate Respiratory Chain Supercomplex

Journal of the Chinese Chemical Society, EarlyView.
In this review we deliver a comprehensive structural analysis of the actinobacterial respiratory chain supercomplex and discuss the principles underlying the assembly of its supramolecular architecture. ABSTRACT Proton translocating respiratory chain complexes assemble into supramolecular structures in their native cellular environment, yet the ...
Wei‐Chun Kao, Nick Hiatt, Carola Hunte
wiley   +1 more source

Complex IIa formation and ABC transporters determine sensitivity of OSCC to Smac mimetics. [PDF]

Cell Death Dis
Wang Y, Liu Z, Si Q, Lu W, Song Y, Jin W, Yang X, Li Z, Hu X, Ding L, Jing Y, Weng P, Yu Q, O'Reilly LA, Silke J, Zhang X, Hu Q, Ni Y.   +17 more
europepmc   +1 more source