Potential application of network descriptions for understanding conformational changes and protonation states of ABC transporters. [PDF]
, 2015 The ABC (ATP Binding Cassette) transporter protein superfamily comprises a large number of ubiquitous and functionally versatile proteins conserved from archaea to humans.
Csermely, Péter +5 more
core
Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges
Advanced Functional Materials, EarlyView.Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley +1 more source
The ABC transporter gene family of
BMC Genomics, 2009 Background The large gene superfamily of ABC (ATP-binding cassette) transporters encodes membrane proteins involved in trafficking processes across biological membranes and further essential cell biological functions.
Cunningham Phil +2 more
doaj +1 more source
Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue [PDF]
, 2017 ATP-binding cassette (ABC) transporters play a pivotal role in human physiology, and mutations in these genes often result in severe hereditary diseases.
Albrecht, Christiane +3 more
core
Advanced Functional Materials, EarlyView.The carbon cloth electrode with targeted pyridinic nitrogen doping, achieved via urea pyrolysis, effectively modulates the adsorption of Cr(II) species and enhances electron transfer, leading to significantly improved kinetics of the Cr(II)/Cr(III) reaction. The material demonstrates a high discharge capacity of 689.3 mAh and an energy efficiency of 72.
Jinfeng Yi +9 more
wiley +1 more source
Danio rerio ABC transporter genes abcb3 and abcb7 play a protecting role against metal contamination [PDF]
, 2016 International audienceATP‐binding cassette (ABC) proteins are efflux transporters and some of them are involved in xenobiotic detoxification. The involvement of four zebrafish ABC transporters in cadmium, zinc and mercury detoxification was characterized
Abraham +52 more
core +3 more sources
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
Advanced Functional Materials, EarlyView.A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source
ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice.
PLoS ONE, 2012 BackgroundATP-binding cassette (ABC) transporters are essential regulators of organismic homeostasis, and are particularly important in protecting the body from potentially harmful exogenous substances.
Toni Schumacher +14 more
doaj +1 more source
Karanjin interferes with ABCB1, ABCC1, and ABCG2
Journal of Pharmacy & Pharmaceutical Sciences, 2014 PURPOSE: The prominent ATP-binding cassette (ABC) transporters ABCB1, ABCC1, and ABCG2 are involved in substance transport across physiological barriers and therefore in drug absorption, distribution, and elimination.
Martin Michaelis +5 more
doaj +1 more source
Comparative and functional genomics of the ABC transporter superfamily across arthropods
BMC Genomics, 2021 Background The ATP-binding cassette (ABC) transporter superfamily is comprised predominantly of proteins which directly utilize energy from ATP to move molecules across the plasma membrane.
Shane Denecke +8 more
doaj +1 more source