Results 81 to 90 of about 3,461 (145)

Association of ABC gene profiles with time to progression and resistance in ovarian cancer revealed by bioinformatics analyses

open access: yesCancer Medicine, 2019
Introduction Ovarian cancer (OC) represents a serious disease with high mortality and lack of efficient predictive and prognostic biomarkers. ATP‐binding cassette (ABC) proteins constitute a large family dedicated to active transmembrane transport ...
Karolina Seborova   +9 more
doaj   +1 more source

Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate

open access: yesReproductive Biology and Endocrinology, 2008
Background High dietary intake of selenium or soybean isoflavones reduces prostate cancer risk. These components each affect androgen-regulated gene expression.
Setchell Kenneth DR   +5 more
doaj   +1 more source

Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits

open access: yesNature Communications
A complete goat (Capra hircus) reference genome enhances analyses of genetic variation, thus providing insights into domestication and selection in goats and related species. Here, we assemble a telomere-to-telomere (T2T) gap-free genome (2.86 Gb) from a
Hui Wu   +22 more
doaj   +1 more source

Multidrug Resistance Protein 4 (ABCC4)-mediated ATP Hydrolysis [PDF]

open access: yesJournal of Biological Chemistry, 2004
Zuben E. Sauna   +2 more
openaire   +1 more source

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

open access: yesFrontiers in Pharmacology
Introduction: ATP-binding cassette (ABC) transporters use the hydrolysis of ATP to power the active transport of molecules, but paradoxically the cystic fibrosis transmembrane regulator (CFTR, ABCC7) forms an ion channel.
Guiying Cui   +3 more
doaj   +1 more source

Role of MRP4 (ABCC4) in Platelet Adenine Nucleotide-Storage [PDF]

open access: yesThe American Journal of Pathology, 2010
Gabriele Jedlitschky   +9 more
openaire   +1 more source

Identification of associated single nucleotide polymorphism markers for early prediction of pyometra in companion dogs

open access: yesJournal of Animal Reproduction and Biotechnology
Background: Pyometra, involves pus accumulation that can lead to death if detected late, making early diagnosis and management crucial, and it is more common in older dogs.
Seo Young Bae   +2 more
doaj   +1 more source

Bulk and single-cell transcriptomics for identification of potential diagnostic biomarkers associated with pulmonary arterial hypertension and integrated stress response and experimental validation

open access: yesClinical and Experimental Hypertension
Background Pulmonary arterial hypertension (PAH) is a lethal vascular disorder characterized by irreversible remodeling of the pulmonary arteries, but the systematic role of the integrated stress response (ISR)-related genes (ISR-RGs) in its pathogenesis
Haoran Li   +4 more
doaj   +1 more source

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