Results 71 to 80 of about 4,110 (154)

Effects of Abcc4-morpholino on the mortalities of zebrafish embryos treated with DDT or lindane.

, 2014
(A–B) Death rates of embryos injected with Abcc4 morpholino (Abcc4-MO) and exposed to 100 µg/L DTT or lindane. The controls include wild type (ctrl) and ctrl-MO-injected embryos. Values are expressed as mean ± standard deviation (n = 5).
Xing Lu (1438414), Yong Long (138508), Rongze Sun (670595), Li Lin (111038), Zongbin Cui (138513), Shan Zhong (380109)   +5 more
core   +1 more source

Influence of ABCC2 and ABCC4 Polymorphisms on Tenofovir Plasma Concentrations in Thai HIV-Infected Patients [PDF]

, 2015
Contains fulltext : 153170.pdf (Publisher’s version ) (Open Access)Tenofovir (TFV) is eliminated by renal excretion, which is mediated through multidrug-resistant protein 2 (MRP2) and MRP4, encoded by ABCC2 and ABCC4, respectively ...
Burger, D.M., Thammajaruk, N., Avihingsanon, A., Pengsuparp, T., Mitruk, S., Rungtivasuwan, K., Ruxrungtham, K., Punyawudho, B.   +7 more
core   +1 more source

The Role of DNA Methyltransferases in Urinary System Diseases

Cancer Innovation, Volume 4, Issue 6, December 2025.
Multiple signaling pathways mediated by DNMTs in the formation of renal fibrosis: (a) DNMTs suppress the expression of transcription factor KLF4 by mediating promoter hypermethylation, thereby promoting epithelial–mesenchymal transition and contributing to the development of renal fibrosis; (b) oxidative stress can upregulate the levels of DNMTs, which
Wei Dong, Shengbin Pei, Dacheng Zhu, Cheng Zeng, Yue Qiu, Yuxin Wu, Xinlu Jia, Siqi Zhang, Chao Li, Wenjuan Zhang, Wenbing Zhang, Zhihua Chen   +11 more
wiley   +1 more source

A Single-Nucleotide Polymorphism in ABCC4 Is Associated with Tenofovir-Related Beta2-Microglobulinuria in Thai Patients with HIV-1 Infection.

PLoS ONE, 2016
BackgroundIn Thailand, the combined generic anti-retroviral drug stavudine/lamivudine/nevirapine (d4T/3TC/NVP) has been used to treat human immunodeficiency virus (HIV)-infected individuals since 2001.
Sirirat Likanonsakul, Bussakorn Suntisuklappon, Ravee Nitiyanontakij, Wisit Prasithsirikul, Emi E Nakayama, Tatsuo Shioda, Chariya Sangsajja   +6 more
doaj   +1 more source

Functional and Transcriptional Disruption of Hepatic ABC Transporters by Environmentally Relevant Short‐Chain Per‐ and Polyfluoroalkyl Substances (PFAS)

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 12, December 2025.
Low‐dose short‐chain PFAS exposures enhance hepatic ABC transporter activity and expression, revealing that environmentally relevant concentrations can reprogram xenobiotic transport pathways and potentially influence drug metabolism, bile acid handling, and lipid homeostasis, highlighting a molecular link between chronic PFAS exposure and altered ...
Gracen E. Collier, Ramon Lavado
wiley   +1 more source

Transcriptional expression of zebrafish abcc4 gene.

, 2014
(A) Spatiotemporal expression of abcc4 gene in developing embryos at indicated stages was detected with whole-mount in situ hybridization (WISH). (a) 1 hpf, lateral view; (b) 6 hpf, lateral view with dorsal to the right; (c) 12 hpf, lateral view with ...
Xing Lu (1438414), Yong Long (138508), Rongze Sun (670595), Li Lin (111038), Zongbin Cui (138513), Shan Zhong (380109)   +5 more
core   +1 more source

Down-regulation of ABCC4 Expression in RKO-KD Cell Line by RNA Interference.

, 2014
A: The shRNA construct containing the green fluorescent protein gene indicated successful transfection via lentivirus. The highest infection efficiency was detected at multiplicities of infection of 5 for RKO-KD (upper) and RKO-NC (lower) cells.
Chang Zhang (443676), Rui Chai (509486), Yan Du (229593), Wei Zhang (405), Enda Yu (509489), Xiaoqing Zhang (80417), Guangwen Cao (388963), Junjie Xing (509488), Zhiqi Yu (509485), Xianhua Gao (509487), Chuangang Fu (509490)   +10 more
core   +1 more source

Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease. [PDF]

, 2011
BACKGROUND: Kawasaki disease (KD) is a self limited vasculitis in which host genetics plays a prominent role. To further the understanding of the role of host genetics in KD, a three-stage genetic study was conducted that began with a family linkage ...
Suzuki, Yasuo, Sheng, S., S. Davila, D. Burgner, M. Levin, Breunis, Willemijn, T. Kuijpers, S. Sheng, Newburger, Jane W, Newburger, Jane W., Khor, C.C., Matsubara, T., W. Breunis, Burns, Jane C, Hibberd, Martin L., Burns, Jane C., Burgner, D., T. Matsubara, J. W. Newburger, Matsubara, Tomoyo, Kuijpers, Taco, Wright, Victoria J, Levin, Michael, Y. Suzuki, A. Baker, Breunis, W., null null, US and International Kawasaki Disease Genetics Consortia, Davila, Sonia, Shimizu, C., Hibberd, M.L., Kuijpers, T., Wright, V.J., Levin, M., Burgner, David, C. C. Khor, C. Shimizu, Suzuki, Y., J. C. Burns, Newburger, J.W., Khor, Chiea Chuen, Baker, Annette, Davila, S., Sheng, Stephanie, Burns, J.C., Hibberd, Martin L, Wright, Victoria J., Nourse, Clare, Shimizu, Chisato, M. L. Hibberd, Baker, A., V. J. Wright   +51 more
core   +1 more source

Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC).

PLoS ONE, 2013
Overexpression of multidrug transporters is a well-established mechanism of resistance to chemotherapy, but other changes may be co-selected upon exposure to drugs that contribute to resistance.
Nancy E Caceres, Maarten Aerts, Béatrice Marquez, Marie-Paule Mingeot-Leclercq, Paul M Tulkens, Bart Devreese, Françoise Van Bambeke   +6 more
doaj   +1 more source

Supplementary Figure 6 from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib

, 2013
PDF file - 144K, Influence of Abcc4 on aspirin transport.
Shuiying Hu (10268480), Ken-ichi Fujita (83343), John D. Schuetz (11127821), Alice A. Gibson (10268477), Alex Sparreboom (236030), Lie Li (372905), Laura J. Janke (7498184), Brian D. Furmanski (14989523), Sharyn D. Baker (14918718), Richard T. Williams (14917794)   +9 more
core   +1 more source