Results 81 to 90 of about 3,675 (154)

Association of ABC gene profiles with time to progression and resistance in ovarian cancer revealed by bioinformatics analyses

Cancer Medicine, 2019
Introduction Ovarian cancer (OC) represents a serious disease with high mortality and lack of efficient predictive and prognostic biomarkers. ATP‐binding cassette (ABC) proteins constitute a large family dedicated to active transmembrane transport ...
Karolina Seborova, Radka Vaclavikova, Pavel Soucek, Katerina Elsnerova, Alena Bartakova, Petr Cernaj, Jiri Bouda, Lukas Rob, Martin Hruda, Pavel Dvorak   +9 more
doaj   +1 more source

Telomere-to-telomere genome assembly of a male goat reveals variants associated with cashmere traits

Nature Communications
A complete goat (Capra hircus) reference genome enhances analyses of genetic variation, thus providing insights into domestication and selection in goats and related species. Here, we assemble a telomere-to-telomere (T2T) gap-free genome (2.86 Gb) from a
Hui Wu, Ling-Yun Luo, Ya-Hui Zhang, Chong-Yan Zhang, Jia-Hui Huang, Dong-Xin Mo, Li-Ming Zhao, Zhi-Xin Wang, Yi-Chuan Wang, EEr He-Hua, Wen-Lin Bai, Di Han, Xing-Tang Dou, Yan-Ling Ren, Renqing Dingkao, Hai-Liang Chen, Yong Ye, Hai-Dong Du, Zhan-Qiang Zhao, Xi-Jun Wang, Shan-Gang Jia, Zhi-Hong Liu, Meng-Hua Li   +22 more
doaj   +1 more source

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

Frontiers in Pharmacology
Introduction: ATP-binding cassette (ABC) transporters use the hydrolysis of ATP to power the active transport of molecules, but paradoxically the cystic fibrosis transmembrane regulator (CFTR, ABCC7) forms an ion channel.
Guiying Cui, Kerry M. Strickland, Analia J. Vazquez Cegla, Nael A. McCarty   +3 more
doaj   +1 more source

Identification of associated single nucleotide polymorphism markers for early prediction of pyometra in companion dogs

Journal of Animal Reproduction and Biotechnology
Background: Pyometra, involves pus accumulation that can lead to death if detected late, making early diagnosis and management crucial, and it is more common in older dogs.
Seo Young Bae, Gwang Hyeon Lee, Hong Sik Kong   +2 more
doaj   +1 more source

ABCC4 Gene [PDF]

, 2020
openaire   +1 more source

ABCC4 wt Allele [PDF]

, 2020
openaire   +1 more source

Integrating machine learning and GWAS for variant prioritization in the INCIPE cohort highlights ABC transporter genes in chronic kidney disease. [PDF]

Front Genet
Dramane D, Treccani M, Veschetti L, Koffi NBS, Patuzzo C, Ferraro PM, Gambaro G, Noel DD, Malerba G.   +8 more
europepmc   +1 more source

ABCC4 rs3741206基因对慢性肾病患者阿托伐他汀代谢及降脂效果的影响

Zhongguo shiyan zhenduanxue
目的 探讨ATP结合盒转运蛋白C4 rs3741206基因型对慢性肾病患者阿托伐他汀代谢及降脂效果的影响。方法 选取2022年1月至2023年6月期间江苏大学附属医院收治的120例慢性肾病患者作为研究对象，所有患者均给予阿托伐他汀(20 mg/d)治疗；患者在接受治疗6周后利用UPLC-MS/MS测定血浆阿托伐他汀(AT)及其代谢产物水平；检测患者ABCC4 rs3741206基因型并比较不同基因型患者AT及其代谢产物水平、血脂控制情况、不良反应等差异。结果 ABCC4 rs3741206包含AA、AC、
鲁雨辰
doaj  

Duodenal mucosal RNA-Seq identifies coordinated bile acid-axis transcriptional alterations in food-responsive enteropathy in dogs. [PDF]

Front Vet Sci
Mózes B, Kiss G, Fóthi Á, Ferenczi S, Psáder R.   +4 more
europepmc   +1 more source

Multidrug Resistance Protein 4 (ABCC4)-mediated ATP Hydrolysis [PDF]

Journal of Biological Chemistry, 2004
Zuben E. Sauna, Krishnamachary Nandigama, Suresh V. Ambudkar   +2 more
openaire   +1 more source