MRP6 (ABCC6) Detection in Normal Human Tissues and Tumors [PDF]
Laboratory Investigation, 2002 Scheffer, George L. +5 more
openaire +3 more sources
405 Adenovirus-mediated ABCC6 gene therapy prevents ectopic mineralization in an Abcc6 mouse model of pseudoxanthoma elasticum [PDF]
Journal of Investigative Dermatology, 2019 J. Huang +4 more
openaire +1 more source
Genomic partitioning and functional dissection of inbreeding depression for stature in Brown Swiss cattle. [PDF]
Genet Sel EvolHe Q +4 more
europepmc +1 more source
ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype. Cellular and
, 2017 BACKGROUND: Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists.
Miglionico R +6 more
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BPS2025 - De-orphanization of ABCC6 by metabolic crude-extract screening
Vascular calcification (VC) is a significant contributor to cardiovascular diseases, particularly in aging populations and patients with type II diabetes or chronic kidney disease. Despite its prevalence, effective treatments for VC remain limited due to
Holm, Caroline Marcher +2 more
core +1 more source
Whole-exome sequencing identifies matrisomal gene associations in monogenic cerebral small vessel disease. [PDF]
J NeurolGuyler SK +6 more
europepmc +1 more source
Generalized Arterial Calcification of Infancy (GACI): State of the Art and Clinical Perspectives. [PDF]
J Cardiovasc Dev DisCastaldi B +3 more
europepmc +1 more source
ABCC6 mutations in pseudoxanthoma elasticum: an update including eight novel ones
, 2008 Purpose: Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder of connective tissue, affecting the retina, the skin, and the cardiovascular system. PXE is caused by mutations in ABCC6.
Plomp, Astrid S. +8 more
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