Results 41 to 50 of about 4,476 (134)

ABCG5 gene responses to treadmill running with or without administration of Pistachio atlantica in female rats [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s): ABC transporters comprise a large family of transmembrane proteins that use the energy provided by ATP hydrolysis to translocate a variety of substrates across biological membranes. All members of the human ABCG subfamily, except for ABCG2,
Abbass Ghanbari-Niaki, Navabeh Zare Kookandeh, Asghar Zare Kookandeh   +2 more
doaj  

اثر هم‌زمان تمرین هوازی تداومی با شدت متوسط و عصاره سبوس برنج بر بیان ژن‌های ABCG5 و ABCG8 بافت روده در موش‌های صحرایی تغذیه‌شده با غذای چرب [PDF]

مجله علوم پزشکی صدرا
مقدمه: هموستاز کلسترول در مسیر جذب روده‌ای تحت تأثیر بیان ژن‌های متفاوتی مانند ABCG5 و ABCG8 قراردارد، لذا هدف از انجام این مطالعه بررسی تأثیر هوازی تداومی با شدت متوسط و عصاره سبوس برنج بر بیان ژن‌های ABCG5 و ABCG8 بافت روده در موش‌های صحرایی تغذیه‌شده ...
هانیه روانبخش, محمدعلی آذربایجانی, حسین فتح اللهی, مقصود پیری, صالح رحمتی احمدآباد   +4 more
doaj   +1 more source

Sterol Metabolism in Ovariectomized Rats: Potential Roles of Campesterol and 4β‐Hydroxycholesterol in Osteoporosis

Lipids, Volume 61, Issue 1, Page 151-162, January 2026.
ABSTRACT Osteoporosis is characterized by low bone mass and microarchitectural deterioration of bone tissue. Lipid metabolism disorders may contribute to osteoporosis in postmenopausal women. Phytosterols and oxysterols (OC) are involved in lipid metabolism.
Wenzhao He, Sayuri Eguchi, Sen Wang, Yasutake Tanaka, Masao Sato   +4 more
wiley   +1 more source

Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8

Journal of Lipid Research, 2002
Mammalian physiological processes can distinguish between dietary cholesterol and non-cholesterol, retaining very little of the non-cholesterol in their bodies.
Kangmo Lu, Mi-Hye Lee, Hongwei Yu, Yuehua Zhou, Shelley A. Sandell, Gerald Salen, Shailendra B. Patel   +6 more
doaj   +1 more source

Sitosterolemia: A Case Report and a Concise Literature Review

Case Reports in Endocrinology, 2023
Background. Sitosterolemia is a relatively rare metabolism lipid disorder, with about 110 cases worldwide and only a few known cases from the Middle East. Sitosterolemia is characterized by excessive uptake of phytosterols and their deposition in various
Moeber M. Mahzari
doaj   +1 more source

A De Novo Splicing Mutation of SRP72 in Bone Marrow Failure Syndrome Type 1: Case Report and Review of the Literature

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study reports a rare case of bone marrow failure syndrome type 1 (BMFS1) caused by a novel de novo splicing mutation (c.1502+1G>A) in the SRP72 gene. The 6‐year‐old patient presented with aplastic anemia and pancytopenia. Genetic analysis identified the mutation, which was absent in both parents, confirming its de novo origin.
Wang Xiangwen, Zhang Duo, Hao Wenjing, Hou Hui   +3 more
wiley   +1 more source

Emodin Improved the Hepatic Metabolic Dysfunction Induced by High Plant‐Protein Diet in Pengze Crucian Carp (Carassius auratus var. Pengze)

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
High plant‐protein (HP) diets could induce bile acid (BA) imbalance and lipid metabolism disorder in fish, and emodin supplementation has been reported to increase serum BA levels and improve lipid metabolism with a lack of understanding of its underlying mechanism.
Kaikai Shen, Yongfa Huang, Zhenwei Lu, Jianqin Li, Jingjie Zhang, Ao Luo, Baoqing Hu, Jingen Xu, Jiamin Li, Chungen Wen, Gang Yang, Chuanpeng Zhou   +11 more
wiley   +1 more source

GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in metabolic dysfunction-associated steatohepatitis livers [PDF]

Clinical and Molecular Hepatology
Background/Aims Metabolic dysfunction-associated steatohepatitis (MASH) is a significant risk factor for gallstone formation, but mechanisms underlying MASH-related gallstone formation remain unclear.
Yi-Tong Li, Wei-Qing Shao, Zhen-Mei Chen, Xiao-Chen Ma, Chen-He Yi, Bao-Rui Tao, Bo Zhang, Yue Ma, Guo Zhang, Rui Zhang, Yan Geng, Jing Lin, Jin-Hong Chen   +12 more
doaj   +1 more source

Genetic regulation of cholesterol absorption and plasma plant sterol levels

Journal of Lipid Research, 2003
The molecular basis of the processes that control two closely related traits, the absorption of cholesterol from the intestines and plasma plant sterol levels, are only partially understood. The discovery that mutations in two novel hemitransporters, ATP
Ephraim Sehayek
doaj   +1 more source

Inhibition of Intestinal Cholesterol Absorption by Ocimum sanctum L. Flower Aqueous Extract via Changing Physicochemical Properties of Cholesterol Micelles

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Hyperlipidemia is recognized as a major contributor to chronic noncommunicable diseases. The primary strategy regarding hyperlipidemia prevention is involved in the blockade of intestinal cholesterol absorption. Ezetimibe (Eze) is the sole prescribed drug that targets Niemann‐Pick C1 Like 1 (NPC1L1), a key cholesterol transporter, resulting in reduced ...
Jakkapong Inchai, Atcharaporn Ontawong, Kongkiat Trisuwan, Kornwalai Tunkaew, Pannita Holasut, Thanthakan Saithong, Thippawan Yasanga, Chutima S. Vaddhanaphuti, Anupama Bose   +8 more
wiley   +1 more source