Results 261 to 270 of about 372,775 (305)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Evaluation of Corneal Irregular Astigmatism and Visual Quality Following Bilateral Sequential SMILE and LASEK: A Six-Year Comparative Study. [PDF]

J Ophthalmol
Li H, Hu W, Li M, Shi Y, Sun L, Ma X, Zou J.   +6 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Hadamard based single-pixel microscopy using sensor-less adaptive optics supported by multi-actuator adaptive lens. [PDF]

Nat Commun
Tobón-Maya H, Willstatter L, Zapata-Valencia SI, Bonora S, Tajahuerce E, Lancis J.   +5 more
europepmc   +1 more source

Characterization of cytostatic drug responses and signaling aberrations in chronic lymphocytic leukemia

, 2016
Ida Kristin Myhrvold
openalex   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Myopic and Astigmatic Laser in situ Keratomileusis Using a Ray Tracing-Based Treatment Algorithm with a Personalized Ablation Profile. [PDF]

Clin Ophthalmol
Krueger RR, Thompson V, Solomon K, Wexler SA, Clinch TE, Whitman J, Moyes A, Price F, Gordon M.   +8 more
europepmc   +1 more source

Mirror symmetry of peripheral aberrations for the eyes of iso- and aniso-myopes (Conference Abstract)

, 2016
Uchechukwu Levi Osuagwu, David A. Atchison, Marwan Suheimat   +2 more
openalex   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Authors' Response to comment on "Impact of intraocular lens decentration and tilt on higher-order aberrations in patients with high and super-high myopia following cataract surgery". [PDF]

Indian J Ophthalmol
Wang Y, Zang B, Bi Q, Huang J, Xu W, Dai C, Ding X, Li D, Zhou Z.   +8 more
europepmc   +1 more source