Results 271 to 280 of about 372,775 (305)

Integrated bio-chemo-cyclostratigraphy of early Eocene carbon cycle aberrations from the Northern Negev

Agnese Mannucci, Chris D. Fokkema, Claudia Agnini, Or M. Bialik, Yannick F. Bats, A. Marí, Basse Theijse, Henk Brinkhuis, Liam Kelly, Nicolás Waldmann, Appy Sluijs, Simone Galeotti, Research Programme in Earth Sciences Utrecht (DES / IVAU), Marine palynology and palaeoceanography, Utrecht Centre for Climate, Life & Oceans (UCCLO, in development)   +14 more
openalex   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Influence of Lens Systematic Errors on Autocollimator Angle Measurement: Theoretical and Experimental Explanations. [PDF]

Sensors (Basel)
Li Y, Zhang S, Chang D, Yu T, Tan J.
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Intravital mesoscale optical imaging: challenges, techniques, and future perspectives. [PDF]

Biophys Rep
Wang M, Wu J, Dai Q.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Ocular higher order aberrations: A comparison between myopes and emmetropes.

Oman J Ophthalmol
Govind I, Antony CL, Jacob SC, Kalikivayi V.   +3 more
europepmc   +1 more source

Visual outcome of a diffractive trifocal intraocular lens in eyes with short axial length. [PDF]

BMC Ophthalmol
Qin R, Liu Y, Shen Z, Liu D, Li Z, Sun Z, Qi H.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Experimental Verification of Model-Based Wavefront Sensorless Adaptive Optics System for Large Aberrations. [PDF]

Micromachines (Basel)
Yang H, Miao Y, Chen P, Zhang Z, Yan Z.
europepmc   +1 more source