Results 11 to 20 of about 2,457 (208)
Undefining life's biochemistry: implications for abiogenesis. [PDF]
In the mid-twentieth century, multiple Nobel Prizes rewarded discoveries of a seemingly universal set of molecules and interactions that collectively defined the chemical basis for life. Twenty-first-century science knows that every detail of this Central Dogma of Molecular Biology can vary through either biological evolution, human engineering ...
Freeland S.
europepmc +5 more sources
The HOMO-LUMO Gap as Discriminator of Biotic from Abiotic Chemistries [PDF]
Low-molecular-mass organic chemicals are widely discussed as potential indicators of life in extraterrestrial habitats. However, demarcation lines between biotic chemicals and abiotic chemicals have been difficult to define.
Roman Abrosimov, Bernd Moosmann
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Reproducible Ala-Gly oligomerization catalyzed by the natural Borate colemanite in prebiotic conditions [PDF]
The abiogenesis of complex peptides is a yet unsolved problem concerning the origin of life, as it is unclear how specific amino acid sequences could be formed in the absence of a regulation mechanism.
Isabella Rimoldi +8 more
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Exploring the space of self-reproducing ribozymes using generative models [PDF]
Estimating the plausibility of RNA self-reproduction is central to origin-of-life scenarios. However, this property has been shown in only a handful of catalytic RNAs.
Camille N. Lambert +8 more
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Positive Microbiology in the Movies. [PDF]
How ‘Positive Microbiology’ is portrayed in commercial movies and its potential as a tool for education and engaging general audiences to counteract germaphobia. Image done with freepik. ABSTRACT Microbes are essential for sustaining life in our planet.
Sánchez-Angulo M.
europepmc +2 more sources
Additional Remarks on Abiogenesis [PDF]
SINCE my communication in NATURE, March 20, a further investigation of the subject has shown me that the experiments there recorded do not yet fully prove the reality of abiogenesis. My argumentation based on those experiments is liable to the following objection:—
David Huizinga
openalex +3 more sources
Xeno Amino Acids: A Look into Biochemistry as We Do Not Know It
Would another origin of life resemble Earth’s biochemical use of amino acids? Here, we review current knowledge at three levels: (1) Could other classes of chemical structure serve as building blocks for biopolymer structure and catalysis?
Sean M. Brown +2 more
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The “Odd Inches”: Moby-Dick’s Fossil Record and Melville’s Admeasured Time
This paper considers the measurements of fossils and markers of geologic time as they appear throughout Moby-Dick, complicating histories of bodies and their remainders. Looking for instances where Ishmael’s measurements fall short or fail to include the
Ryan Heryford
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Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics [PDF]
A sudden transition in a system from an inanimate state to the living state—defined on the basis of present day living organisms—would constitute a highly unlikely event hardly predictable from physical laws.
Robert Pascal +2 more
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The Future of Origin of Life Research: Bridging Decades-Old Divisions
Research on the origin of life is highly heterogeneous. After a peculiar historical development, it still includes strongly opposed views which potentially hinder progress.
Martina Preiner +24 more
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