Results 111 to 120 of about 149,179 (300)

An Abnormal Human Hemoglobin (Hb Rampa) Found in Nagasaki

open access: yes, 1989
この報告はヒト異常ヘモグロビンHb Rampa についての我国最初の詳細な記載である.PaulingがHbSを報告して以来,Hb 分子の機能や遺伝の面から多くの種類のヒト異常ヘモグロビンが報告されている.我々は長崎在住の男性のHb α鎖の異常を電気泳動で見出し,部分精製したα鎖のトリプシン消化物をフィンガープリント法で検索したが,異常を発見できなかった.このためHbを化学修飾後にCM‐セルロース・カラムクロマトを行なう方法で正常と異常α鎖を分離し得ることを見出した ...
Matsuda, Genji   +3 more
core  

Percent of HIV-uninfected and HIV-infected infants with normal and abnormal hemoglobin, Kisumu Breastfeeding study, Kisumu, Kenya, July 2003- February, 2009.

open access: yes, 2016
Percent of HIV-uninfected and HIV-infected infants with normal and abnormal hemoglobin, Kisumu Breastfeeding study, Kisumu, Kenya, July 2003- February, 2009.
Richard Lando (450377)   +11 more
core   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo   +3 more
wiley   +1 more source

Comparison of the Relationship between Preoperative Hemoglobin Level and Acute Renal Failure in Patients Undergoing Noncardiac Surgery

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: Acute renal failure is one of the problems among hospitalized patients in different parts of the hospital, which, if not considered, will increase patient costs, length of hospitalization, and mortality rate; identification of factors ...
Parvin Sajedi, Leili Mahdian
doaj  

Cerebrospinal Fluid from Restless Legs Syndrome Patients Reduces Iron Uptake in Blood–Brain Barrier Endothelial Cells by Disrupting the Regulation of Transferrin Receptors

open access: yesAnnals of Neurology, EarlyView.
Model figure of BBBECs TfR1 regulation in control and RLS: Graphical representation of TfR1 regulation in ECs by IRPs and representing it can be dysregulated by miR‐124‐3p in ECs of RLS. FPN1, ferroportin; BBBEC, blood‐brain barrier endothelial cells; IRP, iron regulatory proytein1/2; TfR1, Transferrin receptor; IRE, Iron responsive elements; Tf ...
Kondaiah Palsa   +6 more
wiley   +1 more source

Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers

open access: yesAnnals of Neurology, EarlyView.
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang   +45 more
wiley   +1 more source

Contribuição para a estimativa da freqüência populacional da Persistência Hereditária da Hemoglobina Fetal no Brasil

open access: yesCadernos de Saúde Pública
Persistência Hereditária de Hemoglobina Fetal (PHHF) é uma condição clinicamente benigna, caracterizada pela síntese contínua da HbF na vida adulta, sem alterações hematológicas. A PHHF funciona como um modulador de gravidade em várias hemoglobinopatias,
Vânia Aparecida da Costa   +3 more
doaj  

PATTERN OF THALASSEMIAS AND OTHER HEMOGLOBINOPATHIES: A STUDY IN DISTRICT DERA ISMAIL KHAN, PAKISTAN

open access: yesGomal Journal of Medical Sciences, 2014
Background: Thalassemia is used to describe disorders with a significant decrease in the rate of synthesis of a globin chain. The term hemoglobinopathy is used to indicate those disorders with structurally abnormal hemoglobin.
Javaid Hussain   +4 more
doaj  

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

A Simple Method for Detection of Chain Anomaly of Abnormal Hemoglobin in Hemolysate without Preliminary Purification

open access: yes
A new simple and rapid method for determining chain anomaly of abnormal hemoglobin was invented. Hemolysate, without preliminary separation and purification of the abnormal hemoglobin, is treated with p-chloromercuribenzoic acid (PCMB) in acidic solution,
Miyaji, Takaoki   +2 more
core  

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