Results 111 to 120 of about 9,952,723 (204)
Immunotherapy mythbusters in head and neck cancer: The abscopal effect and pseudoprogression.
, 2019 Atypical patterns of response to immunotherapy have been observed, including the abscopal effect and pseudoprogression. Although both are infrequent in head and neck squamous cell carcinoma, the synergism between radiation and checkpoint blockade therapy
Dunn, L., Lauber, K.
core +1 more source
Advances in the Role of Chemokines in Microwave Ablation‐Based Combinatorial Immunotherapy
Cancer Science, EarlyView.MWA can initiate antitumor immunity through tumor antigen release and innate immune activation, but iMWA may instead promote an immunosuppressive microenvironment. Combining MWA with immunotherapeutic strategies offers a promising approach to enhance systemic immunity and suppress residual and distant tumors.
Ruijie An, Ningning He, Wendong Gu
wiley +1 more source
Anti-PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma [PDF]
, 2019 BACKGROUND Most glioblastoma recurrences occur near prior radiation treatment sites. Future clinical success will require achieving and optimizing an 'abscopal effect', whereby un-irradiated neoplastic cells outside treatment sites are recognized and ...
Durfy, Sharon J +18 more
core +1 more source
Advanced Oncology, Volume 1, Issue 1, December 2026.Messenger RNA constructs encoding nontumor antigens are proposed to sensitize cold tumors to checkpoint blockade. Observational survival estimates favor vaccination but are heterogeneous, and bias‐focused analyses find no significant difference once time‐zero is aligned. Epitope spreading remains undemonstrated in humans. This review separates what the
Sarfaraz K. Niazi
wiley +1 more source
The Need to Deepen the Abscopal Effect and Synergy among Radiotherapy and Immunotherapy
, 2018 Emerging data that radiotherapy can potentially convert the patient’s own tumor into an in situ vaccine have raised significant interest for testing radiation in combination with immunotherapy.
Nerina Denaro, Denaro Nerina*
core +1 more source
Comparison of two close‐packing methods for vertex placement in lattice radiotherapy (LRT)
Journal of Applied Clinical Medical Physics, Volume 27, Issue 11, November 2026.Abstract Background Lattice Radiation Therapy (LRT) is characterized by its 3D‐mouldated spatial dose distribution of vertices inside the lattice volume with high peak‐to‐valley dose ratio (PVDR) for enhancing tumor control and reducing normal tissue toxicity.
Yingjie Song, Pan Ma, Jianrong Dai
wiley +1 more source
Abscopal Effect of Radiotherapy in the Immunotherapy Era: Systematic Review of Reported Cases
, 2019 Mounting evidence suggests that radiation stimulates the immune system and this contributes to the abscopal effect, which is defined as "response at a distance from the irradiated volume." Though identified more than 50 years ago, the abscopal effect is ...
Karaman, Sule +3 more
core +1 more source
Use of synchrotron medical microbeam irradiation to investigate radiation-induced bystander and abscopal effects in vivo [PDF]
, 2015 The question of whether bystander and abscopal effects are the same is unclear. Our experimental system enables us to address this question by allowing irradiated organisms to partner with unexposed individuals.
Bräuer-Krisch, Elke +15 more
core +2 more sources
Immunization by Radiotherapy: Enhancing an Immune-mediated Abscopal Effect [PDF]
, 2018 Radiotherapy aims to destroy tumors by inducing DNA damage in their cells at the local irradiation site. Its immune-mediated systemic effects, called abscopal effect, has shown to enhance anti-tumor immunity when combined with immune therapies and thus ...
Steffen, Amy
core +1 more source
BMC CancerBackground The synergistic suppressive effects of the radioimmunotherapy-induced abscopal effect on distant non-irradiated tumors have recently emerged as a research hotspot.
Hui Wang +5 more
doaj +1 more source