Results 121 to 130 of about 9,952,723 (204)

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

open access: yesClinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang   +8 more
wiley   +1 more source

Abscopal Effect: Propitious or Pernicious?

open access: yesThe journal of contemporary dental practice, 2018
Recent advances in the field of radiation biology have increased our knowledge of cellular responses to radiation and microenvironmental disseminations through radiation at molecular level.
Sachin C, Sarode   +3 more
openaire   +1 more source

Tumor‐Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy–Immunotherapy Combination Trials

open access: yesInternational Journal of Cancer, Volume 159, Issue 8, Page 1857-1872, 15 October 2026.
ABSTRACT Clinical trials combining radiotherapy (RT) with immune checkpoint blockade (ICB) have shown improved outcomes in only a fraction of patients, and optimal strategies for integrating these modalities remain under intense investigation. With a few exceptions, phase III combination trials have yielded disappointing results.
Xuanwei Zhang   +10 more
wiley   +1 more source

Abscopal effect in maxillary sinus cancer: Insights from two case reports and a literature review

open access: yesCancer Reports
Background The abscopal effect is a rare phenomenon in which localized radiation therapy triggers tumor reduction in nontargeted areas. Although this phenomenon has been observed in various cancer types, it remains infrequent and not fully understood ...
Akihiro Sakai   +6 more
doaj   +1 more source

Abscopal effect in melanoma: effective treatment in situ may unlock systemic antitumor immunity

open access: yesAcademia Oncology
The abscopal effect—where localized treatment, typically radiotherapy, triggers regression of distant metastatic tumors—remains a rare yet clinically impactful phenomenon in solid tumor oncology.
John D. Mitsou, Vivian Tseveleki
doaj   +1 more source

Radiotherapy-Activated Hafnium Oxide Nanoparticles Produce Abscopal Effect in a Mouse Colorectal Cancer Model

open access: yesInternational Journal of Nanomedicine, 2020
Ping Zhang,* Audrey Darmon,* Julie Marill, Naeemunnisa Mohamed Anesary, Sébastien Paris Nanobiotix, Paris, France*These authors contributed equally to this workCorrespondence: Sébastien Paris Email sebastien.paris@nanobiotix.comPurpose ...
Zhang P   +4 more
doaj  

Experimental model for the irradiation-mediated abscopal effect and factors influencing this effect

open access: yes
Radiotherapy (RT) is the primary treatment for cancer. Ionizing radiation from RT induces tumor damage at the irradiated site, and, although clinically infrequent, may cause regression of tumors distant from the irradiated site-a phenomenon known as the ...
山田, 敦   +27 more
core  

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