Results 111 to 120 of about 2,104,112 (314)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Relative and absolute poverty : the case of México, 1992-2004 [PDF]

open access: yes, 2005
This paper advocates that although an absolute notion of poverty should remain an essential ingredient in the evaluation of the standard of living in developing and transition economies, it is time that relative poverty begins to be systematically ...
Ruiz-Castillo, Javier   +1 more
core  

Philosophical Interpretation of “God Is Dead”: Retreat, Disruption, and Judgment

open access: yesReligions
Nietzsche’s declaration of “God is dead” signifies not only the collapse of classical metaphysical systems in philosophy but also shifts in the psychological structure of individuals and society after the secularization of Christianity.
Kuo Li
doaj   +1 more source

Color Difference and Memory Recall in Free-Flying Honeybees: Forget the Hard Problem

open access: yesInsects, 2014
Free-flying honeybees acquire color information differently depending upon whether a target color is learnt in isolation (absolute conditioning), or in relation to a perceptually similar color (differential conditioning).
Adrian G. Dyer, Jair E. Garcia
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Chapter 7 Absolute Orientation of Single Images

open access: yes, 2008
mining the 9 unknowns. However, these equations are nonlinear in the nine unknowns, the direct solution of all the unknowns from the minimum number of 5 control points is not available, or probably not existent.
Absolute Orientation
core  

Interferometer for the IMGC rise-and-fall absolute gravimeter

open access: yes, 2002
Absolute gravity measurements are performed by absolute gravimeters that sometimes show significant differences between their averaged values, as borne out by the international comparisons organized periodically by the Bureau International des Poids et ...
Desogus S   +2 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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