Results 201 to 210 of about 106,890 (293)

Fig Leaf Bioactivity and Safety: Temperature Optimization and FTIR Authentication. [PDF]

Food Sci Nutr
Vasupen E, Rabpairee K, Toommuangpak W, Sompeerapun O, Chaiwong U, Yuthachit P, Kachenpukdee N, Nawong S, Thaiwong N.   +8 more
europepmc   +1 more source

Changing From the Top: New Outsider CEO and TMT Structure Change

British Journal of Management, EarlyView.
Abstract Understanding how new CEOs change top management teams (TMTs) is central to explaining post‐succession outcomes. We examine how new outsider CEOs change the TMT's structural interdependence, which refers to the horizontal, vertical and reward linkages that influence collaboration and coordination.
Can Aktan, Maximilian Weis
wiley   +1 more source

Non-targeted metabolomics reveals tissue-specific metabolic profiling and antioxidant - related markers in <i>Mosla chinensis</i> Maxim. cv. Jiangxiangru. [PDF]

Front Plant Sci
Wang Y, Zhang J, Wang M, Cheng J, Yan W.
europepmc   +1 more source

Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian, Lena Palaniyappan, Theodore T. Kolivakis, Howard C. Margolese   +3 more
wiley   +1 more source

Selective small molecule targeting of KDM4 as a therapeutic strategy to reduce proliferation of acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Summary Acute myeloid leukaemia (AML) is an aggressive disease with poor survival and high relapse rates. Coupled with the complex mutational burden observed, there is an unmet clinical need for more targeted therapies. Epigenetic therapies have shown promise both as monotherapy and in combination strategies and specifically histone lysine demethylase,
Laura Monaghan, Roderick P. Bunschoten, Joana Bittencourt‐Silvestre, Taeju Park, Susan Gannon, Petrisor Alin Pirvan, Alex Hoose, Helen Wheadon, Robert M. J. Liskamp, Xu Huang, Heather G. Jørgensen   +10 more
wiley   +1 more source

Starch Aldehyde-Theaflavin Conjugate: Synthesis, Structure, and Antioxidant and Antimicrobial Activities. [PDF]

Foods
Shao Y, Cheng Y, Ye X.
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

IAP Antagonists Selectively Eliminate Therapy‐Induced Senescent Cancer Cells via TNFα‐Independent Apoptosis

Cancer Science, EarlyView.
Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa, Takeshi Wakasa, Yuki Kataoka, Koji Ando, Eiji Oki, Yoshihiko Maehara, Makoto Iimori, Hiroyuki Kitao   +7 more
wiley   +1 more source