Results 181 to 190 of about 108,976 (291)

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre   +5 more
wiley   +1 more source

Activating Paper Applying Gelatin, Starch and Chitosan Coatings Loaded With O/W Emulsions Encapsulating Rutin, Carvacrol and α‐Tocopherol

open access: yesPackaging Technology and Science, EarlyView.
Emulsion type governed the microstructure and functionality of papers coated with biopolymers matrix loaded with hydrophobic bioactives encapsulated into O/W emulsions. Emulsified systems improved UV–Vis barrier and antioxidant activity, whereas gelatin coatings with conventional or Pickering emulsions provided the greatest mechanical reinforcement ...
Kamila de L. Santos   +4 more
wiley   +1 more source

External Stimuli‐Activable Single‐Atom Nanozymes for Bioapplications

open access: yesSmall, EarlyView.
Stimuli‐activable single‐atom nanozymes (SANs) are reviewed from materials design to biomedical applications. We explain electronic‐structure tuning principles and synthesis strategies that maximize the responsiveness of metal active sites and supports to light, ultrasound, and magnetic fields.
Hyun Ko   +6 more
wiley   +1 more source

Activatable smart contrast agents for photoacoustic imaging

open access: yesSmart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh   +5 more
wiley   +1 more source

Oxophilic Yb2O3 nanoparticles as radical scavengers to enhance the durability of Fe–N–C oxygen reduction catalysts

open access: yesSmart Molecules, EarlyView.
Fe–N–C catalysts suffer from radical attack during oxygen reduction. By immobilizing oxophilic Yb2O3 nanoparticles near Fe–N4 sites as efficient radical scavengers, the catalyst achieves enhanced activity and stability. Abstract The practical application of Fe–N–C catalysts in proton exchange membrane fuel cells is substantially limited by their ...
Jiayu Liu   +4 more
wiley   +1 more source

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