Results 261 to 270 of about 110,272 (342)

Neurophysiological Effect of Transcutaneous Electrical Spinal Cord Stimulation in Chronic Complete Spinal Cord Injury

open access: yesArtificial Organs, EarlyView.
TESCS‐ABT induced neurophysiological changes in individuals with chronic complete SCI, however these did not consistently translate into functional improvements. These findings highlight the role of residual supraspinal connectivity and inform future research to optimise this neurotechnology for SCI rehabilitation and identify likely responders ...
E. L. McNicol   +6 more
wiley   +1 more source

The BH3‐only protein NOXA is essential for apoptosis induction by BH3‐mimetics targeting BCL2 or BCL‐XL in DLBCL

open access: yesBritish Journal of Haematology, EarlyView.
Summary BCL2 inhibitors (BCL2i) have transformed the management of chronic lymphocytic leukaemia (CLL), but their use in more aggressive B‐cell malignancies such as diffuse large B‐Cell lymphoma (DLBCL) is complicated by the more heterogeneous nature of the disease.
Nahide Yildirim   +7 more
wiley   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

Changes in Key Biodiversity Area networks following national comprehensive assessments

open access: yesConservation Biology, EarlyView.
Making comprehensive assessments of Key Biodiversity Area (KBA) networks in a country greatly increases their number and area. Countries that have not yet done so will be missing about half of these globally significant sites and missing the opportunity to get 30 × 30 conservation in the right places. Abstract Key Biodiversity Areas (KBAs) are sites of
Andrew J. Plumptre   +46 more
wiley   +1 more source

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