Results 51 to 60 of about 74,738 (303)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Effects of power electronics devices on the energy quality of an administrative building [PDF]

, 2019
This paper proposes the analysis of the effects of power electronics devices on the energy quality of an administrative building. For the study a method is applied that allows the analysis of the main problems of energy quality such as voltage ...
Gómez Sarduy, Julio R., Viego Felipe, Percy R., Viego, Percy R., Quispe, Enrique C., Sarmiento Crespo, Paulo Cesar, Viego, Percy, Sarmiento, Paulo, Silva, Jorge I., Enrique C. Quispe, Paulo Sarmiento, Sousa Santos, Vladimir, Sarmiento Crespo, Paulo César, Sousa, Vladimir, Silva Ortega, Jorge Iván, Quispe Oqueña, Enrique Ciro, Quispe, Enrique Ciro, Gómez Sarduy, Julio Rafael, Percy R. Viego, Jorge I. Silva, Vladimir Sousa, Julio R. Gómez, Gómez, Julio R.   +21 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Comparison of Electrical Load Performance betweenSS4B and HXD2 Electric Locomotive

机车电传动, 2014
HXD2 and SS4B were selected as the representative of AC drive and DC drive electric locomotive respectively. Based on theactual measured data, their electrical load performance were compared in four aspects, i.e. working principle, power factor, harmonic
WANG Shi-shan, WU Ming-li, XUE Jiao
doaj  

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

An Integrated Multifunctional Bidirectional AC/DC and DC/DC Converter for Electric Vehicles Applications

Energies, 2016
This paper presents an on-board vehicular battery charger that integrates bidirectional AC/DC converter and DC/DC converter to achieve high power density for application in electric vehicles (EVs).
Liwen Pan, Chengning Zhang
doaj   +1 more source

The Latest High Performance AC Drive Systems.

JAPAN TAPPI JOURNAL, 1997
AC drive system has been developed to achieve the high performance and reliability. A high voltage and large capacity IGBT inverter has been launched and it widely covers applications of paper machines, winders and etc. The higher productivity and quality are required, the more important AC drive system becomes in pulp and paper industries.
openaire   +2 more sources

Ventilation System of HXD2B Locomotive

机车电传动, 2011
The ventilation system of high-power AC drive electrical locomotive HXD2B was introduced. Considering its uniqueness, descriptions was provided from filtering device, ventilating structure and ventilation facilities etc of locomotive ventilation system ...
任广慧
doaj