Results 71 to 80 of about 55,672 (306)
, 2021 Higher education institutions are facing growing pressure to improve retention and graduation rates. Academic analytics has emerged as a strategy to address the completion issue.
Dumont, Kristy Chene
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Ubiquity ProceedingsLearning analytics have gained relevance in online higher education over the last decade, focusing on supporting teaching and learning processes while enhancing students’ academic performance.
José Israel Reyes +3 more
doaj +1 more source
Safety in Numbers: Developing a Shared Analytics Services for Academic Libraries
, 2015 Purpose It is clear that libraries consider the use of data to inform decision making a top priority in the next five years. Jisc’s considerable work on activity data has highlighted the lack of tools and services for libraries to exploit this data.
Showers, Ben, Stone, Graham
core
Towards Analytics for Wholistic School Improvement: Hierarchical Process Modelling and Evidence Visualization [PDF]
, 2017 Central to the mission of most educational institutions is the task of preparing the next generation of citizens to contribute to society. Schools, colleges, and universities value a range of outcomes — e.g., problem solving, creativity, collaboration ...
Steven Barr +5 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source