Results 91 to 100 of about 253,180 (311)
Quality of Diabetes Care in U.S. Academic Medical Centers: Low rates of medical regimen change [PDF]
, 2005 To assess both standard and novel diabetes quality measures in a national sample of U.S.
Meigs, J. B., Grant, R. W., Buse, J. B.
core +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Initiatives to Engage Private-Practice Physicians in the Mission of Academic Medical Centers [PDF]
, 2003 Today\u27s healthcare market presents many challenges to academic healthcare centers and community-based physicians given the constrained resources and competition for healthcare dollars.
Appleby, Douglas C.
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Policy on Posthumous Sperm Retrieval: Survey of 75 Major Academic Medical Centers [PDF]
, 2018 To evaluate the presence and content of policies on posthumous sperm retrieval at 75 major academic medical centers in the U.S. We surveyed the top 75 major academic medical centers ranked for research in 2016 by U.S.
Nancy L. Brackett +9 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Private Practicing Physician-Investigator: Ethical Implications of Clinical Research in the Office Setting [PDF]
, 2002 Drug companies are moving their research from academic medical centers to physicians' private offices. The shift brings in more subjects, and could mean faster and better results. It also changes the physician's relationship to patients, dangles monetary
Klein, Jason E., Fleischman, Alan R.
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Physician Assistant and Nurse Practitioner Utilization in Academic Medical Centers [PDF]
, 2011 The purpose of this study was to collect information on the utilization of physician assistants (PAs) and nurse practitioners (NPs) in academic health centers.
Marc Moote +3 more
core +1 more source