Results 61 to 70 of about 27,122 (201)

Opportunistic free: Living amoeba now becoming a usual pathogen?

Indian Journal of Pathology and Microbiology, 2017
Acanthamoeba species cause granulomatous Acanthamoeba encephalitis in immunocompromised patients. We report a case of acute purulent meningoencephalitis with a focal neurological deficit caused by Acanthamoeba species in a 2 years immunocompetent child.
Dnyaneshwari Purushottam Ghadage, Archana Chintaman Choure, Archana Bhimrao Wankhade, Arvind Vamanrao Bhore   +3 more
doaj   +1 more source

An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment

Parasite, 2015
Free-living amoebae of the genus Acanthamoeba are causal agents of a severe sight-threatening infection of the cornea known as Acanthamoeba keratitis. Moreover, the number of reported cases worldwide is increasing year after year, mostly in contact lens ...
J. Lorenzo-Morales, N. Khan, J. Walochnik   +2 more
semanticscholar   +1 more source

Supercationic Poly(Hexamethylene Biguanide)‐Derived Carbon Dots for Combating Multidrug‐Resistant Bacterial Keratitis

Small Structures, Volume 7, Issue 3, March 2026.
This research introduces poly(hexamethylene biguanide)‐derived carbon dots (P‐CDs) as a novel antibacterial agent for combating multidrug‐resistant bacterial keratitis. P‐CDs exhibit potent activity against resistant pathogens, including MRSA and MRPA. In vivo results confirm their superior therapeutic efficacy over standard antibiotics, alongside the ...
Wenjie Fan, Tianji Feng, Hongxian Pan, Yin Zhang, Zhebin Chen, Qiao Jin, Haijie Han, Jian Ji, Ke Yao   +8 more
wiley   +1 more source

Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba

Scientific Reports, 2017
The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sight-threatening infection of the eye and the almost universally fatal granulomatous amoebic encephalitis. More effective treatments are required.
Scott Thomson, Christopher A. Rice, Tong Zhang, RuAngelie Edrada-Ebel, Fiona L. Henriquez, Craig W. Roberts   +5 more
doaj   +1 more source

Acanthamoeba keratitis: confirmation of the UK outbreak and a prospective case-control study identifying contributing risk factors

British Journal of Ophthalmology, 2018
Background/aims Acanthamoeba keratitis (AK) is a chronic debilitating corneal infection principally affecting contact lens (CL) users. Studies were designed to test claims that the UK incidence may have increased in 2012–2014 and to evaluate potential ...
Nicole A. Carnt, J. Hoffman, S. Verma, S. Hau, C. Radford, D. Minassian, J. Dart   +6 more
semanticscholar   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Development of an Ex Vivo Porcine Eye Model for Exploring the Pathogenicity of Acanthamoeba

Microorganisms
Acanthamoeba, a widely distributed free-living amoeba found in various environments, is an opportunistic pathogen responsible for causing Acanthamoeba keratitis, a condition that may lead to blindness.
Ming-Der Shi, Ko-Chiang Sung, Jian-Ming Huang, Chun-Hsien Chen, Yu-Jen Wang   +4 more
doaj   +1 more source

Isolation and molecular identification of Acanthamoeba spp. from hospital dust and soil of Khomein, Iran, as reservoir for nosocomial infection.

Parasite Epidemiology and Control, 2021
Background: Acanthamoeba spp. are commonest opportunistic amoebae, which ubiquitous in various environmental resources. Acanthamoeba species are the causative agents of amoebic keratitis, granulomatous amoebic encephalitis and i.e.
Behnam Abedi, Davood Azadi, Reza Hajihossein, Sahar Khodashenas, Kazem Ghaffari, Mahdi Mosayebi   +5 more
doaj   +1 more source

Description of Virulent Factors and Horizontal Gene Transfers of Keratitis-Associated Amoeba Acanthamoeba Triangularis by Genome Analysis

Pathogens, 2020
Acanthamoeba triangularis strain SH 621 is a free-living amoeba belonging to Acanthamoeba ribo-genotype T4. This ubiquitous protist is among the free-living amoebas responsible for Acanthamoeba keratitis, a severe infection of human cornea.
I. Hasni, J. Andreani, P. Colson, B. La Scola   +3 more
semanticscholar   +1 more source

Microbial Distributions Across Wide‐Ranging Temperature Gradients of Hot Springs in Thailand: A Review of 35 Years of Research on Hot Spring‐Associated Microorganisms

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This review article summarised 35 years of research on microbial distributions (bacteria, archaea and microbial eukaryotes) across wide‐ranging hot spring temperatures in Thailand, including the overall research progression, scopes and methodologies of previous studies.
C. Sriaporn, K. Phinyo, U. Sompong, J. Pekkoh, J. Homnan, S. Komonjinda   +5 more
wiley   +1 more source