Results 31 to 40 of about 8,808 (199)

Phragmites australis (Cav.) Trin. ex Steud. Extract Induces Apoptosis-like Programmed Cell Death in Acanthamoeba castellanii Trophozoites

Plants, 2022
Acanthamoeba keratitis (AK) is an infectious ocular disease which is difficult to diagnose correctly and cure. Development of an effective and safe therapeutic drug for AK is needed.
Hương-Giang Lê, Ji-Su Choi, Buyng-Su Hwang, Yong-Tae Jeong, Jung-Mi Kang, Tuấn-Cường Võ, Pyo-Yun Cho, Young-Kyung Lee, Won-Gi Yoo, Yeonchul Hong, Young-Taek Oh, Byoung-Kuk Na   +11 more
doaj   +1 more source

Targeting Acanthamoeba proteins interaction with flavonoids of Propolis extract by in vitro and in silico studies for promising therapeutic effects [version 3; peer review: 2 approved]

F1000Research, 2023
Background: Propolis is a natural resinous mixture produced by bees. It provides beneficial effects on human health in the treatment/management of many diseases.
Tooba Mahboob, Polrat Wilairatana, Mohammed Rahmatullah, Karma G. Dolma, Maria de Lourdes Pereira, Christophe Wiart, Madhu Gupta, Chea Sin, Tajudeen O. Jimoh, Sónia M.R. Oliveira, Alok K. Paul, Najme Sadat Abtahi, Watcharapong Mitsuwan, Rachasak Boonhok, Roghayeh Norouzi, Julalak Chuprom, Suthinee Sangkanu, Veeranoot Nissapatorn, Abolghasem Siyadatpanah, Imran Sama-ae, Sirirat Surinkaew   +20 more
doaj   +1 more source

Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds [PDF]

, 2007
Tubulin is essential to eukaryotic cells and is targeted by several antineoplastics, herbicides, and antimicrobials. We demonstrate that Acanthamoeba spp.
Henriquez, Fiona L., Ingram, Paul R., Muench, Stephen P., Rice, David W., Roberts, Craig W.   +4 more
core   +2 more sources

Dataset of cathepsin L-like CP inhibition of Naegleria fowleri and Acanthamoeba castellanii by ppTvCP4r from Trichomonas vaginalis

Data in Brief, 2018
The recombinant TvCP4 prepro region (ppTvCP4r) acts as an exogenous inhibitor of cathepsin L-like CPs from Trichomonas vaginalis (Cárdenas-Guerra et al., 2015 [1]). Here, we present the dataset of the trichomonad ppTvCP4r inhibitory effect against the CP
Rosa E. Cárdenas-Guerra, Moisés Martínez-Castillo, Jaime Ortega-López, Mineko Shibayama, Rossana Arroyo   +4 more
doaj   +1 more source

Stable transfection of Acanthamoeba castellanii

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005
A simple method for stable transfection of Acanthamoeba castellanii using plasmids which confer resistance to neomycin G418 is described. Expression of neomycin phosphotransferase is driven by the Acanthamoeba TBP gene promoter, and can be monitored by cell growth in the presence of neomycin G418 or by Western blot analysis.
Peng, Zhihua, Omaruddin, Romaica, Bateman, Erik   +2 more
openaire   +2 more sources

Acanthamoeba activates macrophages predominantly through toll-like receptor 4 and MyD88-dependent mechanisms to induce Interleukin IL-12 and IL-6 [PDF]

, 2017
Acanthamoeba castellanii is a free-living ubiquitous amoeba, with a worldwide distribution, that can occasionally infect humans, causing particularly severe infections in immune compromised individuals.
Alexander, James, Cano, Antonella, Henriquez, Fiona L., Mattana, Antonella, Roberts, Craig W., Woods, Stuart   +5 more
core   +2 more sources

The Effect of Plasma Activated Water on Acanthamoeba castellanii

Journal of Ardabil University of Medical Sciences, 2021
Background & Objectives: Cold Plasma is an emerging non-thermal, chemical-free, environmentally friendly disinfection technology. Plasma-activated water has received considerable attention from researchers in recent years.
Mojtaba Darvishi, Somayeh Bahrami, Mehdi Zarei, Mohammad Sabaeian   +3 more
doaj  

Tracking amino acid’s uptake into the protozoan Acanthamoeba castellanii by stable-isotope labelling and Raman spectral imaging [PDF]

, 2016
The capacity of pathogens to acquire nutrients from their host cells is one of the most fundamental aspects of infection biology. Hence, measuring the patterns of nutrients’ uptake by pathogens is essential for understanding the interactions of pathogens
Muñoz, Neff, Pascut, Paszko-Kolva, Van
core   +2 more sources

Targeting Acanthamoeba proteins interaction with flavonoids of Propolis extract by in vitro and in silico studies for promising therapeutic effects [version 2; peer review: 2 approved]

F1000Research, 2023
Background: Propolis is a natural resinous mixture produced by bees. It provides beneficial effects on human health in the treatment/management of many diseases.
Tooba Mahboob, Polrat Wilairatana, Mohammed Rahmatullah, Karma G. Dolma, Maria de Lourdes Pereira, Christophe Wiart, Madhu Gupta, Chea Sin, Tajudeen O. Jimoh, Sónia M.R. Oliveira, Alok K. Paul, Najme Sadat Abtahi, Watcharapong Mitsuwan, Rachasak Boonhok, Roghayeh Norouzi, Julalak Chuprom, Suthinee Sangkanu, Veeranoot Nissapatorn, Abolghasem Siyadatpanah, Imran Sama-ae, Sirirat Surinkaew   +20 more
doaj   +1 more source

Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51) [PDF]

, 2015
Herein, we have investigated the amebicidal activities of the pharmaceutical triazole CYP51 inhibitors fluconazole, itraconazole, and voriconazole against Acanthamoeba castellanii and Acanthamoeba polyphaga and assess their potential as therapeutic ...
Andrew G. S. Warrilow, David C. Lamb, Diane E. Kelly, Josie E. Parker, Nicola J. Rolley, Stephen N. Smith, Steven L. Kelly, W. David Nes   +7 more
core   +1 more source