Results 41 to 50 of about 8,808 (199)
International Journal for Parasitology: Drugs and Drug Resistance, 2016 Acanthamoeba castellanii is a free-living protozoan pathogen capable of causing a blinding keratitis and fatal granulomatous encephalitis. Current treatment generally involves an hourly application of polyhexamethylene biguanide (PHMB) over a period of ...
Fu-Chin Huang +5 more
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Microorganisms, 2022 Although the prevalence of Acanthamoeba keratitis (AK) is rare, its incidence in contact lens wearers has increased. Acanthamoeba infections can lead to the loss of vision if the diagnosis and treatment are delayed.
Min-Jeong Kim +7 more
doaj +1 more source
Acanthamoeba castellanii (genotype T4) stimulates the production of interleukin-10 as well as pro-inflammatory cytokines in THP-1 cells, human peripheral blood mononuclear cells and human monocyte-derived macrophages [PDF]
, 2016 Free-living amoebae of the genus Acanthamoeba can cause severe and chronic infections in humans, mainly localized in immune privileged sites, as the brain and the eye.
Cano, Antonella +8 more
core +2 more sources
Antiamoebic Properties of Ceftriaxone and Zinc-Oxide–Cyclodextrin-Conjugated Ceftriaxone
Antibiotics, 2022 Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent.
Zinb Makhlouf +6 more
doaj +1 more source
Acanthamoeba and bacteria produce antimicrobials to target their counterpart [PDF]
, 2014 Background In the microbial ecosystem, microbes compete for space and nutrients. Consequently, some have developed the ability to kill or inhibit the growth of other competing microbes by producing antimicrobial substances.
Iqbal, Junaid +2 more
core +2 more sources
Acanthamoeba castellanii exhibits intron retention during encystment
Parasitology Research, 2022 Intron retention (IR) refers to the mechanism of alternative splicing in which an intron is not excised from the mature transcript. IR in the cosmopolitan free-living amoeba Acanthamoeba castellanii has not been studied. We performed an analysis of RNA sequencing data during encystment to identify genes that presented differentially retained introns ...
De Obeso Fernandez Del Valle, Alvaro +2 more
openaire +3 more sources
Scientific Reports, 2017 The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sight-threatening infection of the eye and the almost universally fatal granulomatous amoebic encephalitis. More effective treatments are required.
Scott Thomson +5 more
doaj +1 more source
Pathogens, 2023 Acanthamoeba keratitis is almost universally associated with contact lens (CL) use. Until today, however, CL solution manufacturing protocols lack testing of anti-amoebic activity.
Anna C. Randag +7 more
doaj +1 more source
Status of the effectiveness of contact lens disinfectants in Malaysia against keratitis-causing pathogens [PDF]
, 2017 The aim of this study was (i) to assess the antimicrobial effects of contact lens disinfecting solutions marketed in Malaysia against common bacterial eye pathogens and as well as eye parasite, Acanthamoeba castellanii, and (ii) to determine whether ...
Farhat Abjani, * +3 more
core +1 more source
Establecimiento de protocolos de cultivo y mantenimiento de Acanthamoeba castellanii
CedamazEl género Acanthamoeba abarca diversas especies de amebas de vida libre, se aíslan con frecuencia de distintas fuentes ambientales como el agua, el suelo y el aire. Varias especies son conocidas por causar infecciones y enfermedades en humanos y animales.
Daniela Román +3 more
doaj +1 more source