Acanthamoeba Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs [PDF]
Expert Review of Anti-Infective Therapy, 2021 Introduction: Acanthamoeba encompasses several species of free-living ameba encountered commonly throughout the environment. Unfortunately, these species of ameba can cause opportunistic infections that result in Acanthamoeba keratitis, granulomatous ...
B. Shing +3 more
semanticscholar +3 more sources
Interpretable deep learning for diagnosis of fungal and acanthamoeba keratitis using in vivo confocal microscopy images [PDF]
Sci Rep, 2023 Infectious keratitis refers to a group of corneal disorders in which corneal tissues suffer inflammation and damage caused by pathogenic infections. Among these disorders, fungal keratitis (FK) and acanthamoeba keratitis (AK) are particularly severe and ...
Mahmoud Essalat +4 more
semanticscholar +2 more sources
Diagnosis of Acanthamoeba Keratitis: Past, Present and Future [PDF]
Diagnostics (Basel), 2023 Acanthamoeba keratitis (AK) is a painful and sight-threatening parasitic corneal infection. In recent years, the incidence of AK has increased. Timely and accurate diagnosis is crucial during the management of AK, as delayed diagnosis often results in ...
Matthew Azzopardi +5 more
semanticscholar +2 more sources
Challenges in Acanthamoeba Keratitis: A Review [PDF]
J Clin Med, 2021 To review challenges in the diagnosis and management of Acanthamoeba keratitis (AK), along with prognostic factors, in order to help ophthalmologists avoid misdiagnosis, protracted treatment periods, and long-term negative sequelae, with an overarching ...
Giuseppe Varacalli +6 more
semanticscholar +2 more sources
Homology Modeling, Molecular Docking, Molecular Dynamic Simulation, and Drug-Likeness of the Modified Alpha-Mangostin against the β-Tubulin Protein of Acanthamoeba Keratitis [PDF]
Molecules, 2022 Acanthamoeba species are capable of causing amoebic keratitis (AK). As a monotherapy, alpha-mangostin is effective for the treatment of AK; however, its bioavailability is quite poor.
Tassanee Ongtanasup +3 more
semanticscholar +2 more sources
Detection of Acanthamoeba spp. using carboxylesterase antibody and its usage for diagnosing Acanthamoeba-keratitis [PDF]
PLoS One, 2022 Contact lens usage has contributed to increased incidence rates of Acanthamoeba keratitis (AK), a serious corneal infection that can lead to blindness.
Min-Jeong Kim +5 more
semanticscholar +2 more sources
Acanthamoeba Keratitis, Pathology, Diagnosis and Treatment
Pathogens, 2021 Acanthamoeba keratitis is an unusual corneal infection that is recently increasing in frequency and is often contracted by contact lens wearers, someone who experienced recent eye trauma, or someone exposed to contaminated waters. Acanthamoeba survive in
Nicholas R. Fanselow +4 more
semanticscholar +1 more source
Evaluation of Acanthamoeba keratitis cases in a tertiary medical care centre over 21 years
Scientific Reports, 2021 To report on Acanthamoeba keratitis cases in a tertiary university eye-hospital in Graz, Austria, over a 21-year period. Retrospective study. Parameters included demographics, diagnostics, clinical courses, medical therapies, surgical interventions ...
Wolfgang List +5 more
semanticscholar +1 more source
Delayed diagnoses of Acanthamoeba keratitis at a tertiary care medical centre
Acta ophthalmologica, 2021 To determine the prevalence and reasons for delays in diagnosis in patients with Acanthamoeba keratitis (AK) presenting to Wilmer Eye Institute, Baltimore, Maryland.
Yesha S Shah +8 more
semanticscholar +1 more source
Open Forum Infectious Diseases, 2023 Background Acanthamoeba is a free-living ameba that can cause severe disease affecting the central nervous system, skin, sinuses, and other organs, particularly in immunocompromised individuals.
Julia C Haston +6 more
semanticscholar +1 more source