Diagnostic considerations for non-Acanthamoeba amoebic keratitis and clinical outcomes [PDF]
, 2022 Cases of amoebic keratitis involving species other than Acanthamoeba are hypothesised to be underdiagnosed and poorly understood. Amoebic keratitis is debilitating and associated with chronic visual impairment.
Henriquez, Fiona L. +2 more
core +1 more source
Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism [PDF]
, 2005 Granulomatous amoebic encephalitis due to Acanthamoeba castellanii is a serious human infection with fatal consequences, but it is not clear how the circulating amoebae interact with the blood-brain barrier and transmigrate into the central nervous ...
Alsam, S. +5 more
core +3 more sources
Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds [PDF]
, 2007 Tubulin is essential to eukaryotic cells and is targeted by several antineoplastics, herbicides, and antimicrobials. We demonstrate that Acanthamoeba spp.
Henriquez, Fiona L. +4 more
core +2 more sources
Should Veterinary Practitioners Be Concerned about Acanthamoeba Keratitis?
, 2021 When presented with an animal exhibiting signs of keratitis (inflammation of the cornea), such as impaired vision, mucoid discharges, redness, swelling, and corneal oedema, most veterinarians would think of bacteria, viruses, or fungi as the potential ...
E. Cooper +2 more
semanticscholar +1 more source
Isolation and genotyping of Acanthamoeba strains from corneal infections in Italy [PDF]
, 2010 Acanthamoeba keratitis (AK) is a corneal disease caused by members of a genus of free-living amoebae and is associated predominantly with contact lens (CL) use. This study reports 16 cases of culture-proven AK diagnosed in northern Italy.
Berrilli, F +8 more
core +3 more sources
The cyclic AMP phosphodiesterase RegA critically regulates encystation in social and pathogenic amoebas [PDF]
, 2014 Amoebas survive environmental stress by differentiating into encapsulated cysts. As cysts, pathogenic amoebas resist antibiotics, which particularly counteracts treatment of vision-destroying Acanthamoeba keratitis. Limited genetic tractability of amoeba
Birgersson, Elin +5 more
core +2 more sources
Results of case-control studies supportthe association between contact lens useand Acanthamoeba keratitis [PDF]
, 2013 Acanthamoeba keratitis (AK) is ever more frequently reported in industrialized countries. The loss of the corneal surface integrity consequent to secondary microtrauma produced by the use of contact lens (CL) favors the penetration of the parasite into ...
BRILLANTE, CHIARA +7 more
core +1 more source
, 2021 This article presents an overview of information regarding Acanthamoeba keratitis per epidemiology, host-pathogen interactions, clinical manifestations, risk factors, environmental implications, diagnosis, treatment and management as well as COVID-19 ...
Chrysanthus Chukwuma
semanticscholar +1 more source
Úlcera bilateral por Acanthamoeba em usuária de lentes de contato gelatinosas descartáveis: um incidente trágico ou uma conseqüência da política agressiva de venda de lentes de contato gelatinosas? [PDF]
, 2008 This is the report of a case of bilateral Acanthamoeba keratitis in a 19-year-old woman who bought a pair of disposable soft contact lenses in a boutique. She wore this same pair of lenses for 3 months daily without the appropriate care.
DIAS, Vanderson Glerian +2 more
core +2 more sources
Ceratites microbianas relacionadas a lente de contato [PDF]
, 2008 PURPOSE: Contact lens-associated microbial keratitis is a severe condition with sight-threatening potential and increasing incidence. Information regarding the etiological agents is essential in guiding management and may vary geographically.
Hofling-Lima, Ana Luisa +1 more
core +3 more sources