Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB. [PDF]
, 2016 Repurposing has gained momentum globally and become an alternative avenue for drug discovery because of its better success rate, and reduced cost, time and issues related to safety than the conventional drug discovery process.
Brindha, Sridharan +4 more
core +1 more source
Pharmacological Treatment of Postprandial Reductions in Blood Pressure : A Systematic Review [PDF]
, 2015 Funded by The Dunhill Medical Trust.
Alam +28 more
core +1 more source
Pharmacy Practice, 2016 Objectives: The primary objective of the study was to assess the mean change in hemoglobin A1c (HbA1c) when acarbose was added to insulin and non-insulin regimens in patients with type 2 diabetes mellitus (T2DM). Secondary objectives were to evaluate the
Wettergreen SA, Sheth S, Malveaux J
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Background: Postprandial hypotension (PPH) is an independent predictive factor of all-cause mortality in older people. Drug management has not achieved a satisfactory effect yet.
Biqing Wang +7 more
doaj +1 more source
Molecular Weight Dependent Glucose Lowering Effect of Low Molecular Weight Chitosan Oligosaccharide (GO2KA1) on Postprandial Blood Glucose Level in SD Rats Model [PDF]
, 2013 This research investigated the effect of enzymatically digested low molecular weight (MW) chitosan oligosaccharide on type 2 diabetes prevention. Three different chitosan oligosaccharide samples with varying MW were evaluated in vitro for inhibition of ...
Apostolidis, Emmanouil +7 more
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α-Glucosidase-Mediated Glucometer Readout for Portable Monitoring of Acarbose and Migliol
Chemosensors, 2022 The α-glucosidase inhibitor is regarded as one of the most important drugs for the treatment of diabetes, which can control postprandial blood glucose levels via prolonging the carbohydrate digestion time and retarding the carbohydrates’ absorption.
Hao Zhang, Feng-Qing Yang
doaj +1 more source
Unlocking the in vitroanti- inflammatory and antidiabetic potential of Polygonum maritimum [PDF]
, 2017 Context: Several Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes. Objective: Evaluate the in vitro antioxidant, anti-inflammatory and antidiabetic potential of methanol and ...
Alice Martins +16 more
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The effect of very low-calorie diets on renal and hepatic outcomes : a systematic review [PDF]
, 2013 Peer reviewedPublisher ...
Broom, J +3 more
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The Safety and Efficacy of Rosa Damascena Extract in Patients with Type II Diabetes: preliminary Report of a Triple Blind Randomized Acarbose Controlled Clinical Trial [PDF]
Journal of Kerman University of Medical Sciences, 2019 Background: Diabetes is a global health problem that its prevalence is increasing rapidly. Rosa damascena extract has shown to have an intensive non-competitive inhibitory effect on α-glucosidase in an animal study.
Mojgan Sanjari +4 more
doaj +1 more source
Engineering of Cyclodextrin Product Specificity and pH Optima of the Thermostable Cyclodextrin Glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1 [PDF]
, 1998 The product specificity and pH optimum of the thermostable cyclodextrin glycosyltransferase (CGTase) from Thermoanaerobacterium thermosulfurigenes EM1 was engineered using a combination of x-ray crystallography and site-directed mutagenesis.
Bauke W. Dijkstra +44 more
core +2 more sources