Results 11 to 20 of about 16,949 (211)

Theoretical Studies for the Discovery of Potential Sucrase-Isomaltase Inhibitors from Maize Silk Phytochemicals: An Approach to Treatment of Type 2 Diabetes

open access: yesMolecules, 2023
A theoretical analysis of the potential inhibition of human sucrase-isomaltase (SI) by flavonoids was carried out with the aim of identifying potential candidates for an alternative treatment of type 2 diabetes. Two compounds from maize silks, maysin and
Linda-Lucila Landeros-Martínez   +5 more
doaj   +1 more source

Structural Insight into a Yeast Maltase—The BaAG2 from Blastobotrys adeninivorans with Transglycosylating Activity

open access: yesJournal of Fungi, 2021
An early-diverged yeast, Blastobotrys (Arxula) adeninivorans (Ba), has biotechnological potential due to nutritional versatility, temperature tolerance, and production of technologically applicable enzymes. We have biochemically characterized from the Ba
Karin Ernits   +5 more
doaj   +1 more source

Acarbose

open access: yesReactions Weekly
INTRODUCTION/BACKGROUNDReactive hypoglycemia, or postprandial hypoglycemia, which can occur during pregnancy due to physiological changes such as altered insulin sensitivity and heightened metabolic needs, presents unique management considerations.
Nurbadriah Jasmiad, Shartiyah Ismail
  +5 more sources

Acarbose for Postprandial Hypotension With Glucose Metabolism Disorders: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Postprandial hypotension (PPH) is an independent predictive factor of all-cause mortality in older people. Drug management has not achieved a satisfactory effect yet.
Biqing Wang   +7 more
doaj   +1 more source

α-Glucosidase-Mediated Glucometer Readout for Portable Monitoring of Acarbose and Migliol

open access: yesChemosensors, 2022
The α-glucosidase inhibitor is regarded as one of the most important drugs for the treatment of diabetes, which can control postprandial blood glucose levels via prolonging the carbohydrate digestion time and retarding the carbohydrates’ absorption.
Hao Zhang, Feng-Qing Yang
doaj   +1 more source

The Safety and Efficacy of Rosa Damascena Extract in Patients with Type II Diabetes: preliminary Report of a Triple Blind Randomized Acarbose Controlled Clinical Trial [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2019
Background: Diabetes is a global health problem that its prevalence is increasing rapidly. Rosa damascena extract has shown to have an intensive non-competitive inhibitory effect on α-glucosidase in an animal study.
Mojgan Sanjari   +4 more
doaj   +1 more source

Gene Cascade Shift and Pathway Enrichment in Rat Kidney Induced by Acarbose Through Comparative Analysis

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Acarbose is an effective anti-diabetic drug to treat type 2 diabetes mellitus (T2DM), a chronic degenerative metabolic disease caused by insulin resistance. The beneficial effects of acarbose on blood sugar control in T2DM patients have been confirmed by
Chun-Yue Weng   +20 more
doaj   +1 more source

Evaluation of Pharmaceutical Compatibility between Acarbose and Common Excipients Used in the Development of Controlled Release Formulations [PDF]

open access: yesPharmaceutical Sciences, 2021
Background: Excipients are used in the formulation of pharmaceutical dosage forms, but mayinteract with active pharmaceutical ingredients (APIs). Some of these interactions could alterthe physicochemical properties of the APIs which can affect the ...
Aiesheh Gholizadeh-Hashjin   +2 more
doaj   +1 more source

Evaluation of the effects of acarbose on weight and metabolic, inflammatory, and cardiovascular markers in patients with obesity and overweight

open access: yesInternational Journal of Preventive Medicine, 2020
Background: Metabolic syndrome (MetS) refers to a cluster of risk factors for cardiovascular disease and type 2 diabetes. The aim of this study is to assess the effects of acarbose as an antihyperglycemic agent (drug) on late complications of MetS ...
Noushin Khalili, Alireza Safavipour
doaj   +1 more source

In Silico Study of a-Amylase and a-Glucosidase Inhibitory Compounds in Aloe vera as Antidiabetic Agent

open access: yesBiotropika: Journal of Tropical Biology, 2023
Type 2 diabetes mellitus (T2DM) is a chronic disease that poses a significant global health issue. The most commonly given drug to treat diabetes is acarbose, which works as an inhibitor of polysaccharide-degrading enzymes, such as alpha amylase dan ...
M. Nizam Zulfi Zakaria   +4 more
doaj   +1 more source

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