Results 91 to 100 of about 9,228,267 (373)
Immunity & Ageing, 2019 The use of Akkermansia muciniphila as potential therapeutic intervention is receiving increasing attention. Health benefits attributed to this bacterium include an improvement of metabolic disorders and exerting anti-inflammatory effects.
B. van der Lugt +10 more
semanticscholar +1 more source
Social disadvantage accelerates aging
Nature MedicineAbstract Social disadvantage, like advanced age, is a risk factor for a broad range of health conditions; however, whether it influences the aging process remains unclear. Here, using a multicohort approach, we investigated the associations of social disadvantage with age-related plasma proteins and age-related diseases.
Kivimäki, M +11 more
openaire +3 more sources
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
The emerging role of cellular senescence in renal diseases [PDF]
, 2020 Cellular senescence represents the state of irreversible cell cycle arrest during cell division. Cellular senescence not only plays a role in diverse biological events such as embryogenesis, tissue regeneration and repair, ageing and tumour occurrence ...
Alpini, Gianfranco +12 more
core +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Some molecular-genetic determinants of premature aging in women
Consilium MedicumBackground. Accelerated biological aging is associated with age-related diseases and an increased risk of mortality. Genetic predisposition may be an important factor in this process. Aim.
Elena V. Kudryavtseva +7 more
doaj +1 more source
Accelerated Aging with Electrical Overstress and Prognostics for Power MOSFETs [PDF]
, 2011 Power electronics play an increasingly important role in energy applications as part of their power converter circuits. Understanding the behavior of these devices, especially their failure modes as they age with nominal usage or sudden fault development
Celaya, Jose Ramon +4 more
core +1 more source
Aging and Disease, 2020 HIV infects the central nervous system and causes HIV/neuroAIDS, which is predominantly manifested in the form of mild cognitive and motor disorder in the era of combination antiretroviral therapy. HIV Tat protein is known to be a major pathogenic factor
Xiaojie Zhao +5 more
semanticscholar +1 more source
Accelerated ageing of molybdenum oxide
Materials Research Express, 2017 The stability and lifetime of materials proposed for photovoltaic applications are important parameters, because such devices should offer long-term reliable performance whilst operating in a harsh environment. In this work, we present a powerful approach to accelerate and study the degradation mechanisms of molybdenum oxide, a material which has shown
Jorge M. +6 more
openaire +3 more sources
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source