Relativity principles in 1+1 dimensions and differential aging reversal
, 2006 We study the behavior of clocks in 1+1 spacetime assuming the relativity principle, the principle of constancy of the speed of light and the clock hypothesis.
A. L. Macdonald +22 more
core +2 more sources
Obesity accelerates cardiovascular ageing
European Heart JournalAbstract A global obesity pandemic, coupled with an increasingly ageing population, is exacerbating the burden of cardiovascular disease. Indeed, clinical and experimental evidence underscores a potential connection between obesity and ageing in the pathogenesis of various cardiovascular disorders. This is further supported by the notion
Ruperez, Celia +4 more
openaire +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Effects of Accelerated Aging and Acid Scarification of Seed Coat with Hydrochloric Acid on Seed Germination Characteristics of Chickpea c.v. Kaka [PDF]
Ikufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2014 To evaluate the effects of accelerated aging and seed coat scarification with Hydrochloric acid (HCl) on seed germination characteristics of chickpea (Cicer arietinum) c.v.
R. Sadrabadi Haghighi
doaj
Accelerated aging for evaluation of vigor in Brachiaria brizantha ‘Xaraés’ seeds
Journal of Seed Science, 2020 : The aim of this study was to adjust the accelerated aging test to evaluate the physiological potential of seed lots of Brachiaria brizantha ‘Xaraés’, represented by four lots.
Ariadne Morbeck Santos Oliveira +4 more
doaj +1 more source
Accelerated Aging with Electrical Overstress and Prognostics for Power MOSFETs [PDF]
, 2011 Power electronics play an increasingly important role in energy applications as part of their power converter circuits. Understanding the behavior of these devices, especially their failure modes as they age with nominal usage or sudden fault development
Celaya, Jose Ramon +4 more
core +1 more source
Experience with Return Voltage Measurements for Assessing Insulation Conditions in Service Aged Transformers [PDF]
, 2003 This paper describes the investigation of the insulation condition of a number of power and distribution type transformers of different manufacturing dates and with different operating histories.
Saha, Tapan K., Yao, Zheng Tong
core +1 more source
Cytomegalovirus infection accelerates epigenetic aging
Experimental Gerontology, 2015 Epigenetic mechanisms such as DNA methylation (DNAm) have a central role in the regulation of gene expression and thereby in cellular differentiation and tissue homeostasis. It has recently been shown that aging is associated with profound changes in DNAm. Several of these methylation changes take place in a clock-like fashion, i.e.
Jylhava Juulia +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Microwave-assisted synthesis of a MK2 inhibitor by Suzuki-Miyaura coupling for study in Werner syndrome cells [PDF]
, 2015 Microwave-assisted Suzuki-Miyaura cross-coupling reactions have been employed towards the synthesis of three different MAPKAPK2 (MK2) inhibitors to study accelerated aging in Werner syndrome (WS) cells, including the cross-coupling of a 2-chloroquinoline
Bagley, Mark C +5 more
core +3 more sources