Results 71 to 80 of about 44,930 (304)

Aging concrete structures: a review of mechanics and concepts [PDF]

, 2018
The safe and cost-efficient management of our built infrastructure is a challenging task considering the expected service life of at least 50 years. In spite of time-dependent changes in material properties, deterioration processes and changing demand by
Wan-Wendner, Roman
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Physical Mechanisms for the Variable Spin-down of SGR 1900+14 [PDF]

, 1999
We consider the physical implications of the rapid spindown of Soft Gamma Repeater 1900+14, and of the apparent "braking glitch", \Delta P/P = l x 10^-4, that was concurrent with the Aug. 27th giant flare.
Duncan, R. C., Finger, M. H., Kouveliotou, C., Thompson, C., van Paradijs, J., Woods, P. M.   +5 more
core   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Interplay between shear loading and structural aging in a physical gel

, 2009
We show that the aging of the mechanical relaxation of a gelatin gel exhibits the same scaling phenomenology as polymer and colloidal glasses. Besides, gelatin is known to exhibit logarithmic structural aging (stiffening). We find that stress accelerates
C. Caroli, L. C. E. Struik, O. Ronsin, S. Kutter, T. Baumberger, V. Normand   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Creep monitoring using permanently installed potential drop sensors [PDF]

, 2015
Creep is the primary life limiting mechanism of static high temperature, high pressure power station components. Creep state evaluation is currently achieved by surface inspection of microstructure during infrequent outages; a methodology which is ...
Corcoran, Joseph
core   +1 more source

‘USDA‐Accelerate’ creeping foxtail, a new creeping foxtail with increased seedling vigor

Journal of Plant Registrations
Abstract The USDA‐ARS announces the release of ‘USDA‐Accelerate’ (Reg. no. CV‐296, PI 706441) creeping foxtail ( Alopecurus arundinaceus Poir.). USDA‐Accelerate is a creeping foxtail with excellent seedling vigor and good herbage dry mass and nutritive value.
Joseph G. Robins, J. Ramsey Buffham
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Creep Behaviour of Modified Mar-247 Superalloy

Archives of Metallurgy and Materials, 2016
The paper presents the results of analysis of creep behaviour in short term creep tests of cast MAR-247 nickel-based superalloy samples made using various modification techniques and heat treatment.
Cieśla M., Mańka M., Binczyk F., Gradoń P.   +3 more
doaj   +1 more source