Results 61 to 70 of about 265,739 (284)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cornea Collagen Cross-linking for Keratoconus: A Comparison between Accelerated and Conventional Methods

Advanced Biomedical Research, 2017
Background: Keratoconus is a progressive degenerative disorder of the cornea in which structural changes in the cornea cause it to become thin and conical in shape.
Hasan Razmjoo, Alireza Peyman, Ali Rahimi, Hoda Jafari Modrek   +3 more
doaj   +1 more source

Topography-guided corneal surface laser ablation combined with simultaneous accelerated corneal collagen cross-linking for treatment of keratoconus

BMC Ophthalmology, 2021
Background to study the outcomes of topography-guided customized excimer laser subepithelial ablation combined with accelerated CXL for progressive keratoconus.
Yu Zhang, Yueguo Chen
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Accelerated Epithelium-Off Corneal Collagen Cross-Linking For Keratoconus: 12-Month Results

Clinical Ophthalmology, 2019
Ismail Ahmed Nagib Omar, Hosny Ahmed Zein Ophthalmology Department, Faculty of Medicine, Minia University, El-Minya, EgyptCorrespondence: Ismail Ahmed Nagib OmarOphthalmology Department, Faculty of Medicine, Minia University, P O Box 61519, El-Minya ...
Omar IAN, Zein HA
doaj  

Conserved Linking in Single- and Double-Stranded Polymers

, 2000
We demonstrate a variant of the Bond Fluctuation lattice Monte Carlo model in which moves through cis conformations are forbidden. Ring polymers in this model have a conserved quantity that amounts to a topological linking number.
Plewa, Joseph S., Witten, Thomas A.
core   +1 more source

Durability of biodegradable polymers for the conservation of cultural heritage [PDF]

, 2019
The use of polymers for conservation of cultural heritage is related to the possibility to slow down or stop natural deterioration which, in many cases, corresponds to stopping the entrance of liquid water and to favor spontaneous water vapor removal ...
Botta L., La Mantia F.P., Megna B., Mistretta M.C., Morreale M., Titone V.   +5 more
core   +2 more sources

Viral Cell Entry Induced by Cross-Linked Decay-Accelerating Factor [PDF]

Journal of Virology, 1998
ABSTRACTDecay-accelerating factor (DAF) mediates cellular attachment for many human picornaviruses. In most cases, viral binding to DAF is itself insufficient to permit cell infectivity, with a second, functional internalization receptor being required to facilitate this process.
openaire   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Paediatric cornea crosslinking current strategies: A review

Advances in Ophthalmology Practice and Research, 2023
Background: In the general population, 1 in 2000 people has keratoconus. Indians and other people from Southeast Asia have a higher incidence of keratoconus.
Pawan Prasher, Ashok Sharma, Rajan Sharma, Vipan K. Vig, Verinder S. Nirankari   +4 more
doaj   +1 more source