Results 61 to 70 of about 4,908,366 (272)

Accelerated versus standard corneal cross linking in the treatment of ectasia post refractive surgery and penetrating keratoplasty: a medium term randomized trial [PDF]

International Journal of Ophthalmology, 2019
AIM: To compare the clinical outcomes of the standard corneal cross linking (CXL) and the accelerated CXL in patients with progressive corneal ectasia post refractive surgery and penetrating keratoplasty.
Hany A. Khairy, Moataz F. Elsawy, Khaled Said-Ahmed, Marwa A. Zaki, Sameh S Mandour   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Protocol for a systematic review, meta-analysis, and trial sequential analysis of clinical outcomes following accelerated versus conventional corneal collagen cross-linking for corneal ectasia

Systematic Reviews, 2019
Background Collagen cross-linking (CXL) is an evolving procedure that enhances the biomechanical rigidity of the cornea and can slow or halt ectatic disease.
Siddharth Nath, Carl Shen, Alex Koziarz, Laura Banfield   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Efficacy of pulsed light accelerated epithelium-off cross-linking in management of keratoconus [PDF]

Egyptian Journal of Clinical Ophthalmology
Background: Corneal collagen cross-linking is an established intervention for halting keratoconus progression. Accelerated protocols have emerged to shorten treatment time, yet the optimal irradiation mode remains debatable.
Thabet, R., Abdel-Radi, M., Mohamed, A., Mostafa, M.   +3 more
doaj   +1 more source

Accelerated and Standard Corneal Cross-Linking Protocols in Patients with Down Syndrome: A Non-inferiority Contralateral Randomized Trial

Ophthalmology and Therapy, 2020
Introduction To compare the results of an accelerated corneal cross-linking (CXL) protocol (9 mW/cm2, 10 min) with the standard CXL protocol (3 mW/cm2, 30 min) in patients with Down syndrome (DS) who have keratoconus (KC).
Hassan Hashemi, Kazem Amanzadeh, Mohammad Seyedian, Hojjat Zeraati, Cynthia J. Roberts, Shiva Mehravaran, Renato Ambrósio, Riccardo Vinciguerra, Paolo Vinciguerra, Soheila Asgari   +9 more
doaj   +1 more source

Peroxidase-mediated cross-linking of bovine a-lactalbumin [PDF]

, 2010
The research presented in this thesis aimed at controlling the horseradish peroxidase-catalyzed cross-linking of bovine α lactalbumin and the implications of this cross-linking for the foam stabilizing properties. Attention is also given to microreactors
Heijnis, W.H.
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A spectroscopic study of the degradation of polyurethane coil coatings. [PDF]

, 2012
PhDThe degradation of polyurethane (PU) coil coatings were studied with step scan phase modulation photo-acoustic (SS-PM-PA) FTIR, confocal Raman mapping (CRM) and scanning electron microscopy (SEM). PU coatings were oven cured for 30 seconds to reach
Zhang, Ying
core   +2 more sources