Results 71 to 80 of about 265,739 (284)

Biomarkers of aging associated with past treatments in breast cancer survivors. [PDF]

, 2017
Radiation and chemotherapy are effective treatments for cancer, but are also toxic to healthy cells. Little is known about whether prior exposure to these treatments is related to markers of cellular aging years later in breast cancer survivors.
Bower, Julienne E, Breen, Elizabeth C, Carroll, Judith E, Chapman, Aaron M, Esquivel, Stephanie, Ganz, Patricia A, Hogan, Matt, Irwin, Michael R, Petersen, Laura, Ramos-Perlberg, Sam, Schiestl, Robert, Scuric, Zorica   +11 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Late Onset Sterile Infiltrate after Accelerated Corneal Cross-Linking

, 2023
ABSTRACT Background: Collagen crosslinking is a therapeutic technique designed to strengthen the cornea and halt the progression of keratoconus. Late onset sterile infiltrate is one of the complications of the corneal Collagen crosslinking. Objective: This study aimed to describe the prevalence, clinical manifestations, potential risk factors and ...
Srwa Sulaiman Ismael, Anwar, Didar Sddeq
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Visual and refractive outcomes of combined excimer laser ablation with accelerated corneal collagen cross-linking in subclinical keratoconus

Saudi Journal for Health Sciences, 2018
Purpose: The purpose of the study was to evaluate efficacy, safety, and stability of visual and refractive outcomes of combined photorefractive keratectomy (PRK) with accelerated corneal collagen cross-linking (CXL) in subclinical keratoconus.
Talal A Althomali
doaj   +1 more source

Alkaline battery containing a separator of a cross-linked copolymer of vinyl alcohol and unsaturated carboxylic acid [PDF]

, 1985
A battery separator for an alkaline battery is described. The separator comprises a cross linked copolymer of vinyl alcohol units and unsaturated carboxylic acid units. The cross linked copolymer is insoluble in water, has excellent zincate diffusion and
Gonzalez-Sanabria, O. D., Hsu, L. C., Philipp, W. H., Sheibley, D. W.   +3 more
core   +1 more source

Internal space structure generalization of the quintom cosmological scenario [PDF]

, 2008
We introduce the Lagrangian for a multi-scalar field configuration in a $N$-dimensional internal space endowed with a constant metric $Q_{ik}$ and generalize the quintom cosmological scenario. We find the energy momentum tensor of the model and show that
A. Einstein, A. Einstein, J. Bernstein, K. Abazajian, L. P. Chimento, Luis P. Chimento, Martín G. Richarte, Mónica Forte, P. F. Gonzalez-Diaz, P. J. Steinhardt, Ruth Lazkoz, S. M. Carroll, V. Sahni   +12 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A novel comparative study of different layered silicate clay types on exfoliation process and final nanostructure of trifunctional epoxy nanocomposites [PDF]

, 2016
© 2016. This version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/The effect of three different organically modified layered silicate clays (Nanomer I.30E, Cloisite 30B and Nanofil SE 3000) on the ...
Calventus Solé, Yolanda, Hutchinson, John M., Shiravand, Fatemeh   +2 more
core   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source