Results 71 to 80 of about 779,523 (368)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

National minimum wage: employed students and the accommodation offset, a consultation [PDF]

open access: yes, 2011
The national minimum wage (NMW) rules allow employers who provide accommodation for workers to count it as a benefit in kind towards payment of the NMW, up to a specified limit.

core  

A Ratio of Accommodative-Convergence to Accommodation in Patients With Refractive Accommodative Esotropia

open access: yesJournal of the Korean Ophthalmological Society, 2010
Purpose: To measure the ratio of accommodative-convergence to accommodation (AC/A ratio) in patients with non- refractive accommodative esotropia in comparison to refractive accommodative esotropia and normal groups. Methods: A total of 43 subjects were divided into 3 groups: the nonrefractive accommodative esotropia group (group 1), the refractive ...
Dong Cheol Lee   +3 more
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

IT-TECHNOLOGIES IN THE PROBLEMS OF IMPROVING EFFICIENCY WITH THE ASSOCIATED START AND SEPARATION OF THE MICRO SATELLITE ON-BOARD SPACE APPARATUS

open access: yesСовременные информационные технологии и IT-образование, 2018
Recently, the study of the near and far space with the help of small spacecraft has become more important. In this regard, we can definitely talk about the whole industry of small space technology, the problems of its creation, application, launch and ...
Aleksandr I. Shulepov
doaj   +1 more source

Uveitis, retinal vasculitis, and loss of accommodation as sole manifestations of demyelinating disease: A case report

open access: yesIndian Journal of Ophthalmology, 2020
In this report we describe nongranulomatous uveitis followed by bilateral retinal vasculitis and much later by the loss of accommodation as initial presentations of demyelinating disease in a 42-year-old female with no other neurologic manifestations ...
Kalpana Babu   +2 more
doaj   +1 more source

Between a Stone and a Hard Place: How the Hajj Can Restore the Spirit of Reasonable Accommodation to Title VII [PDF]

open access: yes, 2013
Although section 701(j) of the Civil Rights Act of 1964 requires that employers reasonably accommodate their employees\u27 religious practices and beliefs, many commentators acknowledge that the spirit of reasonable accommodation has not been realized ...
Mooney, Matthew P.
core   +1 more source

Learning to Match [PDF]

open access: yesarXiv, 2018
Booking.com is a virtual two-sided marketplace where guests and accommodation providers are the two distinct stakeholders. They meet to satisfy their respective and different goals. Guests want to be able to choose accommodations from a huge and diverse inventory, fast and reliably within their requirements and constraints.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Complex therapy of accommodation disturbances in children. Review

open access: yesOftalʹmologiâ, 2014
Different accommodation disturbances in children and adolescents are described. Chronic excess accommodative effort repre- sents stable hypertonus of ciliary muscle due to permanent near visual activity.
E. Yu. Markova   +3 more
doaj  

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